SCHEMBL435704

SCHEMBL435704

Nc1ccc(S(=O)(=O)c2ccc(N)c(Cl)c2)cc1Cl

nearest known ligand 0.73

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA1 P00915 6/20 0.73
CA2 P00918 6/20 0.73
CA9 Q16790 6/20 0.73
CA12 O43570 3/20 0.73
CA4 P22748 3/20 0.73
CA6 P23280 3/20 0.73
CA5A P35218 3/20 0.73
CA7 P43166 3/20 0.73
CA14 Q9ULX7 3/20 0.73
CA5B Q9Y2D0 3/20 0.73
CYP3A4 P08684 6/20 0.55
ALDH1A1 P00352 4/20 0.55
TSHR P16473 4/20 0.55
HTR6 P50406 2/20 0.55
PKM P14618 2/20 0.55
THRB P10828 1/20 0.55
HPGD P15428 1/20 0.55
ALOX15 P16050 1/20 0.55
CASP1 P29466 1/20 0.55
RECQL P46063 1/20 0.55

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7185475 0.92 ALDH1A1 (0.69) CA1CA2CA9CA12CA4
SCHEMBL11112123 0.90 CA12 (0.61) CA1CA2CA9CA12CA4
SCHEMBL4608708 0.89 CA2 (0.59) CA1CA2CA9CA12CA4
SCHEMBL4607820 0.89 CA2 (0.59) CA1CA2CA9CA12CA4
SCHEMBL7195423 0.87 LMNA (0.69) CA1CA2CA9CA12CA4
SCHEMBL7190058 0.86 CA1 (0.56) CA1CA2CA9CA12CA4
SCHEMBL8496857 0.84 CA1 (0.70) CA1CA2CA9CA12CA4
SCHEMBL248783 0.84 CA1 (1.00) CA1CA2CA9CA12CA4
SCHEMBL29906360 0.84 CA1 (1.00) CA1CA2CA9CA12CA4
SCHEMBL303829 0.83 CA1 (0.68) CA1CA2CA9CA12CA4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 215 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3405453-B1 A METHOD FOR PREPARING POLY(CARBONATE-ETH ERIMIDE) COMPOUND PTT GLOBAL CHEMICAL PUBLIC CO LTD (TH) 2024-05-29 EP claimed
WO-2024052724-A1 COATING KIT AND METHOD FOR REPAIR AND/OR RECONSTITUTION OF RUBBER AND/OR METAL WORN AREAS BERTECH PANAMÁ S.A. (PA) 2024-03-14 WO claimed
US-10759904-B2 Method for preparing poly(carbonate-etherimide) compound PTT GLOBAL CHEMICAL PUBLIC COMPANY LIMITED (TH) 2020-09-01 US claimed
US-20190202980-A1 METHOD FOR PREPARING POLY(CARBONATE-ETHERIMIDE) COMPOUND PTT GLOBAL CHEMICAL PUBLIC COMPANY LIMITED (TH) 2019-07-04 US claimed
EP-3405453-A2 A METHOD FOR PREPARING POLY(CARBONATE-ETH ERIMIDE) COMPOUND PTT Global Chemical Public Company Limited (TH) 2018-11-28 EP claimed
US-9248408-B2 Hollow-fiber element for organic-vapor separation UBE INDUSTRIES, LTD. (JP) 2016-02-02 US claimed
US-20070009751-A1 Polyamic acid resin composition modified with laminate nanometer silica sheet and polyimide prepared therefrom CHANG CHUN PLASTICS CO., LTD. (TW) 2007-01-11 US claimed
US-7005163-B2 Organic-inorganic hybrid film material and its fabrication CHANG CHUN PLASTICS CO., LTD. (TW) 2006-02-28 US claimed
EP-1021478-B1 PHTHALONITRILE THERMOSET POLYMERS AND COMPOSITES CURED WITH HALOGEN-CONTAINING AROMATIC AMINE CURING AGENTS and process for producing them US GOV SEC NAVY (US) 2005-01-19 EP claimed
US-20040110014-A1 Organic-inorganic hybrid film material and its fabrication CHANG CHUN PLASTICS CO., LTD. (TW) 2004-06-10 US claimed
EP-1021478-A4 PHTHALONITRILE THERMOSET POLYMERS AND COMPOSITES CURED WITH HALOGEN-CONTAINING AROMATIC AMINE CURING AGENTS US NAVY (US) 2000-12-13 EP claimed
EP-1021478-A1 PHTHALONITRILE THERMOSET POLYMERS AND COMPOSITES CURED WITH HALOGEN-CONTAINING AROMATIC AMINE CURING AGENTS THE GOVERNMENT OF THE UNITED STATES OF AMERICA, as represented by THE SECRETARY OF THE NAVY (US) 2000-07-26 EP claimed
WO-1999018145-A1 PHTHALONITRILE THERMOSET POLYMERS AND COMPOSITES CURED WITH HALOGEN-CONTAINING AROMATIC AMINE CURING AGENTS THE GOVERNMENT OF THE UNITED STATES AS REPRESENTED BY THE SECRETARY OF THE NAVY (US) 1999-04-15 WO claimed
US-4886873-A ELASTICITY AND HEAT RESISTANCE DIRECTOR-GENERAL OF AGENCY OF INDUSTRIAL SCIENCE AND TECHNOLOGY (JP) 1989-12-12 US claimed
EP-3405453-B1 A METHOD FOR PREPARING POLY(CARBONATE-ETH ERIMIDE) COMPOUND PTT GLOBAL CHEMICAL PUBLIC CO LTD (TH) 2024-05-29 EP disclosed
US-20230023657-A1 Phthalonitrile Resins, Methods Of Making Same And Compositions Thereof HUNTSMAN ADVANCED MATERIALS AMERICAS LLC 2023-01-26 US disclosed
US-20220403108-A1 Curable Compositions Of Benzoxazine And Phthalonitrile Resins HUNTSMAN ADVANCED MATERIALS AMERICAS LLC 2022-12-22 US disclosed
US-3996196-A Polyimide-metallo-phthalocyanines and their preparation UNIVERSITY OF NOTRE DAME DU LAC (US) 1976-12-07 US disclosed
US-3987003-A THERMALLY STABLE DIOXO AND DITHIO-BENZISOQUINOLINE COMPOSITIONS AND PROCESS OF SYNTHESIZING SAME THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE AIR FORCE (US) 1976-10-19 US disclosed
US-3960980-A Method of producing elastomer resins BRIDGESTONE TIRE COMPANY LIMITED (JA) 1976-06-01 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230023657-A1 Phthalonitrile Resins, Methods Of Making Same And Compositions Thereof PNN, PAH, CUL4B CA1 3204/4885CA2 2617/4885CA9 3490/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.