SCHEMBL7190058

SCHEMBL7190058

Nc1cc(Cl)cc(S(=O)(=O)c2ccc(N)c(Cl)c2)c1

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA1 P00915 4/20 0.56
CA2 P00918 4/20 0.56
CA9 Q16790 4/20 0.56
CA12 O43570 1/20 0.56
CA4 P22748 1/20 0.56
CA6 P23280 1/20 0.56
CA5A P35218 1/20 0.56
CA7 P43166 1/20 0.56
CA14 Q9ULX7 1/20 0.56
CA5B Q9Y2D0 1/20 0.56
CYP3A4 P08684 7/20 0.47
ALDH1A1 P00352 4/20 0.47
TSHR P16473 4/20 0.47
HTR6 P50406 3/20 0.47
PKM P14618 1/20 0.47
THRB P10828 1/20 0.47
HPGD P15428 1/20 0.47
ALOX15 P16050 1/20 0.47
CASP1 P29466 1/20 0.47
RECQL P46063 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL435704 0.86 CA1 (0.73) CA1CA2CA9CA12CA4
SCHEMBL2808682 0.84 CYP3A4 (0.55) CA1CA2CA9CA12CA4
SCHEMBL7183566 0.82 MEN1 (0.68) CA1CA2CA9CA12CA4
SCHEMBL7185475 0.82 ALDH1A1 (0.69) CA1CA2CA9CA12CA4
SCHEMBL7195423 0.81 LMNA (0.69) CA1CA2CA9CA12CA4
SCHEMBL7181900 0.79 LMNA (0.71) CA1CA2CA9CA12CA4
SCHEMBL11112123 0.77 CA12 (0.61) CA1CA2CA9CA12CA4
SCHEMBL4608708 0.76 CA2 (0.59) CA1CA2CA9CA12CA4
SCHEMBL4607820 0.76 CA2 (0.59) CA1CA2CA9CA12CA4
SCHEMBL7185513 0.73 CYP3A4 (0.61) CA1CA2CA9CA12CA4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20030064235-A1 Optical members made of polymide resins MITSUI CHEMICALS, INC. (JP) 2003-04-03 US disclosed
EP-1237015-A1 OPTICAL MEMBERS MADE OF POLYIMIDE RESINS Mitsui Chemicals, Inc. (JP) 2002-09-04 EP disclosed