Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 1/20 | 0.70 |
| ▸ | CA1 | P00915 | 1/20 | 0.70 |
| ▸ | CA2 | P00918 | 1/20 | 0.70 |
| ▸ | CA3 | P07451 | 1/20 | 0.70 |
| ▸ | CA4 | P22748 | 1/20 | 0.70 |
| ▸ | CA6 | P23280 | 1/20 | 0.70 |
| ▸ | CA5A | P35218 | 1/20 | 0.70 |
| ▸ | CA7 | P43166 | 1/20 | 0.70 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.70 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.70 |
| ▸ | CA9 | Q16790 | 1/20 | 0.70 |
| ▸ | CA13 | Q8N1Q1 | 1/20 | 0.70 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.70 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.70 |
| ▸ | CTSS | P25774 | 10/20 | 0.63 |
| ▸ | CTSK | P43235 | 9/20 | 0.61 |
| ▸ | CTSB | P07858 | 4/20 | 0.61 |
| ▸ | CTSL | P07711 | 2/20 | 0.61 |
| ▸ | ATM | Q13315 | 1/20 | 0.54 |
| ▸ | PPARA | Q07869 | 2/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29611575 | 1.00 | CA12 (0.70) | CA12CA1CA2CA3CA4 | |
| SCHEMBL28736812 | 1.00 | CA12 (0.70) | CA12CA1CA2CA3CA4 | |
| SCHEMBL1290504 | 1.00 | CA12 (0.70) | CA12CA1CA2CA3CA4 | |
| SCHEMBL993498 | 0.90 | CTSS (0.59) | CA12CA1CA2CA3CA4 | |
| SCHEMBL9582887 | 0.89 | CTSS (0.63) | CA12CA1CA2CA3CA4 | |
| SCHEMBL11985033 | 0.89 | CTSS (0.79) | CA12CA1CA2CA3CA4 | |
| SCHEMBL9582058 | 0.89 | CTSS (0.65) | CA12CA1CA2CA3CA4 | |
| SCHEMBL42634 | 0.88 | CTSS (0.62) | CA12CA1CA2CA3CA4 | |
| SCHEMBL30968897 | 0.88 | CTSS (0.62) | CA12CA1CA2CA3CA4 | |
| SCHEMBL3383006 | 0.88 | CTSS (0.77) | CTSSCTSKCTSBCTSLATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 76 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118812395-A | Method for synthesizing lacosamide intermediate | 浙江普洛家园药业有限公司 | 2024-10-22 | — | — | CN | claimed |
| CN-114685317-A | Preparation method of medicine for treating epilepsy | 成都硕德药业有限公司 | 2022-07-01 | — | — | CN | claimed |
| CN-114527205-A | Method for detecting isomer of 2-tert-butyloxycarbonylamino-N-benzyl-3-methoxypropionamide | 石家庄四药有限公司 | 2022-05-24 | — | — | CN | claimed |
| WO-2013024383-A1 | AN IMPROVED PROCESS FOR THE PREPARATION OF LACOSAMIDE | ALEMBIC PHARMACEUTICALS LIMITED (IN) | 2013-02-21 | — | — | WO | claimed |
| US-20110130350-A1 | SYNTHESIS SCHEME FOR LACOSAMIDE | UCB PHARMA GMBH (DE) | 2011-06-02 | — | — | US | claimed |
| EP-1799635-B1 | IMPROVED SYNTHESIS SCHEME FOR LACOSAMIDE | SANOL ARZNEI SCHWARZ GMBH (DE) | 2010-02-17 | — | — | EP | claimed |
| US-20080027137-A1 | Synthesis Scheme for Lacosamide | SCHWARZ PHARMA AG (DE) | 2008-01-31 | — | — | US | claimed |
| EP-1799635-A1 | IMPROVED SYNTHESIS SCHEME FOR LACOSAMIDE | SCHWARZ PHARMA AG (DE) | 2007-06-27 | — | — | EP | claimed |
| WO-2006037574-A1 | IMPROVED SYNTHESIS SCHEME FOR LACOSAMIDE | SCHWARZ PHARMA AG (DE) | 2006-04-13 | — | — | WO | claimed |
| EP-1642889-A1 | Improved synthesis scheme for lacosamide | SCHWARZ PHARMA AG (DE) | 2006-04-05 | — | — | EP | claimed |
| CN-118812395-A | Method for synthesizing lacosamide intermediate | 浙江普洛家园药业有限公司 | 2024-10-22 | — | — | CN | disclosed |
| CN-118812395-A | Method for synthesizing lacosamide intermediate | 浙江普洛家园药业有限公司 | 2024-10-22 | — | — | CN | disclosed |
| CN-118271200-A | Industrial preparation method and application of lacosamide | 北京澳合药物研究院有限公司 | 2024-07-02 | — | — | CN | disclosed |
| CN-115616118-B | High performance liquid chromatography for high performance separation and detection of related substances in D-serine | 北京澳合药物研究院有限公司 | 2023-02-28 | — | — | CN | disclosed |
| CN-115616118-A | High performance liquid chromatography for high performance separation and detection of related substances in D-serine | 北京澳合药物研究院有限公司 | 2023-01-17 | — | — | CN | disclosed |
| EP-1799635-B1 | IMPROVED SYNTHESIS SCHEME FOR LACOSAMIDE | SANOL ARZNEI SCHWARZ GMBH (DE) | 2010-02-17 | — | — | EP | disclosed |
| US-20080027137-A1 | Synthesis Scheme for Lacosamide | SCHWARZ PHARMA AG (DE) | 2008-01-31 | — | — | US | disclosed |
| EP-1799635-A1 | IMPROVED SYNTHESIS SCHEME FOR LACOSAMIDE | SCHWARZ PHARMA AG (DE) | 2007-06-27 | — | — | EP | disclosed |
| WO-2006037574-A1 | IMPROVED SYNTHESIS SCHEME FOR LACOSAMIDE | SCHWARZ PHARMA AG (DE) | 2006-04-13 | — | — | WO | disclosed |
| EP-1642889-A1 | Improved synthesis scheme for lacosamide | SCHWARZ PHARMA AG (DE) | 2006-04-05 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080027137-A1 | Synthesis Scheme for Lacosamide | RIMKLA, GNMT, NAAA | CA12 66/4885CA1 58/4885CA2 76/4885 |
| US-20110130350-A1 | SYNTHESIS SCHEME FOR LACOSAMIDE | RIMKLA, GNMT, MYT1 | CA12 101/4885CA1 56/4885CA2 81/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.