SCHEMBL4357599

SCHEMBL4357599

O=C(c1ccccc1-c1cc(Cl)ncc1Cl)c1ccccc1-c1cc(Cl)ncc1Cl

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
RECQL P46063 1/20 0.41
RORB Q92753 4/20 0.40
RORC P51449 3/20 0.40
GPBAR1 Q8TDU6 3/20 0.39
CES2 O00748 1/20 0.37
CES1 P23141 1/20 0.37
KMT2A Q03164 1/20 0.36
ALDH1A1 P00352 1/20 0.36
POLB P06746 1/20 0.34
MAPK14 Q16539 2/20 0.34
GABRP O00591 1/20 0.34
GABRD O14764 1/20 0.34
GABRA1 P14867 1/20 0.34
GABRB1 P18505 1/20 0.34
GABRG2 P18507 1/20 0.34
GABRB3 P28472 1/20 0.34
GABRA5 P31644 1/20 0.34
GABRA3 P34903 1/20 0.34
GABRA2 P47869 1/20 0.34
GABRB2 P47870 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25753206 0.75 RECQL (0.50) RECQLRORBRORCCES2CES1
SCHEMBL31565655 0.75 RECQL (0.50) RECQLRORBRORCCES2CES1
SCHEMBL5781412 0.72 ALDH1A1 (0.47) KMT2AALDH1A1
SCHEMBL23277118 0.71 CYP1A2 (0.44) RORBRORCALDH1A1GABRPGABRD
SCHEMBL27740453 0.71 HPGD (0.47) KMT2AALDH1A1MAPK14MAPK13MAPK12
SCHEMBL30919693 0.71 CYP2A6 (0.46) KMT2AALDH1A1GABRPGABRDGABRA1
SCHEMBL23277179 0.71 CYP2A6 (0.46) KMT2AALDH1A1GABRPGABRDGABRA1
SCHEMBL28662886 0.70 NNMT (0.42) RECQLRORBRORCKMT2ACYP1A2
SCHEMBL24769729 0.70 SMN1; SMN2 (0.43) RORBRORCALDH1A1
SCHEMBL16502492 0.68 NAPRT (0.46) KMT2APLAU

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1457511-B1 CROSSLINKABLE AROMATIC RESINS HAVING PROTONIC ACID GROUPS AND ION CONDUCTIVE POLYMER MEMBRANES BINDERS AND FUEL CELLS MADE BY USING THE SAME MITSUI CHEMICALS INC (JP) 2009-07-15 EP disclosed
US-7345135-B2 Crosslinkable aromatic resin having protonic acid group, and ion conductive polymer membrane, binder and fuel cell using the resin MITSUI CHEMICALS, INC. (JP) 2008-03-18 US disclosed
US-20040191602-A1 Crosslinkable aromatic resin having protonic acid group, and ion conductive polymer membrane, binder and fuel cell using the resin MITSUI CHEMICALS, INC. (JP) 2004-09-30 US disclosed
EP-1457511-A1 CROSSLINKABLE AROMATIC RESINS HAVING PROTONIC ACID GROUPS AND ION CONDUCTIVE POLYMER MEMBRANES BINDERS AND FUEL CELLS MADE BY USING THE SAME Mitsui Chemicals, Inc. (JP) 2004-09-15 EP disclosed