Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TACR3 | P29371 | 17/20 | 0.47 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.40 |
| ▸ | TACR2 | P21452 | 5/20 | 0.39 |
| ▸ | TACR1 | P25103 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.38 |
| ▸ | MTOR | P42345 | 1/20 | 0.38 |
| ▸ | BLM | P54132 | 1/20 | 0.38 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13619226 | 0.86 | TACR3 (0.53) | TACR3SLC2A1TACR2ADORA2AADORA1 | |
| SCHEMBL4361695 | 0.86 | TACR3 (0.53) | TACR3SLC2A1TACR2CYP1A2CYP3A4 | |
| SCHEMBL4356702 | 0.82 | TACR3 (0.56) | TACR3SLC2A1TACR2TSHRKDM4E | |
| SCHEMBL13619223 | 0.81 | TACR3 (0.54) | TACR3SLC2A1TACR2TSHRKDM4E | |
| SCHEMBL3239756 | 0.79 | CTSS (0.48) | — | |
| SCHEMBL3243514 | 0.77 | UTS2R (0.40) | MEN1KMT2A | |
| SCHEMBL3239589 | 0.76 | L3MBTL1 (0.40) | — | |
| SCHEMBL4355252 | 0.75 | TACR3 (0.53) | TACR3SLC2A1TACR2TSHRKDM4E | |
| SCHEMBL4363718 | 0.72 | TACR3 (0.43) | TACR3SLC2A1TACR2ADORA2AADORA1 | |
| SCHEMBL4357027 | 0.72 | TACR3 (0.46) | TACR3SLC2A1TACR2TSHRKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090286828-A1 | 2-AMINO-1-PHENYLETHYLCARBOXAMIDE DERIVATIVES | GLAXO GROUP LIMITED (GB) | 2009-11-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090286828-A1 | 2-AMINO-1-PHENYLETHYLCARBOXAMIDE DERIVATIVES | PNMT, SLC18A2, COMT | TACR3 2005/4885SLC2A1 1844/4885TACR2 435/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.