SCHEMBL4359074

SCHEMBL4359074

C=CCN1CN(CO)C(=O)N(CO)C1

nearest known ligand 0.37

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
CYP3A4 P08684 1/20 0.37
LMNA P02545 1/20 0.34
GAA P10253 1/20 0.34
ADRA1D P25100 1/20 0.32
ADRA1A P35348 1/20 0.32
ADRA1B P35368 1/20 0.32
NPSR1 Q6W5P4 1/20 0.31
DRD2 P14416 1/20 0.30
SIGMAR1 Q99720 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31469053 0.85 CYP3A4 (0.41) CYP3A4LMNAGAAADRA1DADRA1A
SCHEMBL13241897 0.78
SCHEMBL7885217 0.76 KMT2A (0.32)
SCHEMBL9930180 0.75
SCHEMBL196659 0.72 L3MBTL1 (0.39)
SCHEMBL11337118 0.72 KMT2A (0.43) LMNA
SCHEMBL8773347 0.71 CYP3A4 (0.39) CYP3A4LMNAGAAADRA1DADRA1A
SCHEMBL545962 0.69 ADRA1A (0.39) CYP3A4LMNAGAAADRA1DADRA1A
SCHEMBL7132415 0.69 CYP3A4 (0.38) CYP3A4LMNAGAAADRA1DADRA1A
SCHEMBL3795571 0.69

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 34 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4452606-A Compositions useful for improving the fastness of dyeings on cellulosic substrates: precondensates of N-methylol compound with polyalkylene polyamine-epihalohydrin product SANDOZ LTD. (CH) 1984-06-05 US claimed
US-4439208-A Method for improving the fastness of dyeings with basic dyes on cellulosic substrates SANDOZ LTD. (CH) 1984-03-27 US claimed
US-4438189-A POLYUNSATURATED COMPOUND, CROSSLINKABLE EPOXY OR METHYLOL COMPOUND HOECHST AKTIENGESELLSCHAFT (DE) 1984-03-20 US claimed
US-4436524-A IMPROVING COLORFASTNESS SANDOZ LTD. (CH) 1984-03-13 US claimed
US-20090292038-A1 Flame Retardant Photoimagable Coverlay Compositions and Methods Relating thereto E. I. DU PONT DE NEMOURS AND COMPANY 2009-11-26 US disclosed
US-7618766-B2 Flame retardant photoimagable coverlay compositions and methods relating thereto E. I. DU PONT DE NEMOURS AND COMPANY (US) 2009-11-17 US disclosed
US-7527915-B2 Flame retardant multi-layer photoimagable coverlay compositions and methods relating thereto E. I. DU PONT DE NEMOURS AND COMPANY (US) 2009-05-05 US disclosed
US-20080033090-A1 Flame retardant multi-layer photoimagable coverlay compositions and methods relating thereto U.S. BANK TRUST COMPANY, NATIONAL ASSOCIATION, AS NOTES COLLATERAL AGENT 2008-02-07 US disclosed
US-20070149635-A1 Flame retardant photoimagable coverlay compositions and methods relating thereto U.S. BANK TRUST COMPANY, NATIONAL ASSOCIATION, AS NOTES COLLATERAL AGENT 2007-06-28 US disclosed
US-20050079442-A1 Halo resistent, photoimagable coverlay compositions, having advantageous application and removal properties, and methods relating thereto DUEBER THOMAS E (US) 2005-04-14 US disclosed
US-20040058276-A1 Halo resistent, photoimagable coverlay compositions, having, advantageous application and removal properties, and methods relating thereto E. I. DU PONT DE NEMOURS AND COMPANY 2004-03-25 US disclosed
EP-1400545-A2 Halo resistant photoimagable coverlay compositions E.I. DU PONT DE NEMOURS AND COMPANY (US) 2004-03-24 EP disclosed
US-4484927-A CATIONIC, CONTAINING OQATERNARY NITROGEN AND BRIDGING MELAMINE GROUPS SANDOZ LTD. (CH) 1984-11-27 US disclosed
US-4452606-A Compositions useful for improving the fastness of dyeings on cellulosic substrates: precondensates of N-methylol compound with polyalkylene polyamine-epihalohydrin product SANDOZ LTD. (CH) 1984-06-05 US disclosed
US-4443223-A Composition and method for improving the fastness of direct and reactive dyeings on cellulose-containing substrates SANDOZ LTD. (CH) 1984-04-17 US disclosed
US-4439203-A Process for improving the wetfastness of dyeings, printings and optical brightenings on cellulosic substrates and compositions useful therefor SANDOZ LTD. (CH) 1984-03-27 US disclosed
US-4439208-A Method for improving the fastness of dyeings with basic dyes on cellulosic substrates SANDOZ LTD. (CH) 1984-03-27 US disclosed
US-4438189-A POLYUNSATURATED COMPOUND, CROSSLINKABLE EPOXY OR METHYLOL COMPOUND HOECHST AKTIENGESELLSCHAFT (DE) 1984-03-20 US disclosed
US-4436524-A IMPROVING COLORFASTNESS SANDOZ LTD. (CH) 1984-03-13 US disclosed
WO-1981002423-A1 COLOURING MEANS AND METHOD FOR COLOURING CELLULOSE FIBERS SANDOZ AG (CH) 1981-09-03 WO disclosed