Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGLN3 | Q9H6Z9 | 6/20 | 0.59 |
| ▸ | EGLN1 | Q9GZT9 | 10/20 | 0.52 |
| ▸ | EGLN2 | Q96KS0 | 5/20 | 0.51 |
| ▸ | CYSLTR2 | Q9NS75 | 1/20 | 0.51 |
| ▸ | PTGDR2 | Q9Y5Y4 | 6/20 | 0.47 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.44 |
| ▸ | GCGR | P47871 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4371854 | 0.90 | EGLN3 (0.54) | EGLN3EGLN1EGLN2CYSLTR2 | |
| SCHEMBL4359785 | 0.89 | EGLN3 (0.68) | EGLN3EGLN1EGLN2CYSLTR2PTGDR2 | |
| SCHEMBL4364439 | 0.88 | EGLN3 (0.46) | EGLN3EGLN1EGLN2CYSLTR2PTGDR2 | |
| SCHEMBL4359258 | 0.88 | EGLN3 (0.47) | EGLN3EGLN1EGLN2CYSLTR2PTGDR2 | |
| SCHEMBL4359069 | 0.86 | EGLN3 (0.51) | EGLN3EGLN1EGLN2GCGR | |
| SCHEMBL4362443 | 0.85 | EGLN3 (0.52) | EGLN3EGLN1EGLN2CYSLTR2PTGDR2 | |
| SCHEMBL4363082 | 0.85 | EGLN3 (0.51) | EGLN3EGLN1EGLN2 | |
| SCHEMBL3857678 | 0.84 | EGLN3 (0.60) | EGLN3EGLN1EGLN2CYSLTR2PTGDR2 | |
| SCHEMBL4358358 | 0.84 | EGLN3 (0.45) | EGLN3EGLN1EGLN2CYSLTR2PTGDR2 | |
| SCHEMBL4365040 | 0.81 | EGLN3 (0.48) | EGLN3EGLN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2124565-A2 | N-SUBSTITUTED GLYCINE DERIVATIVES: HYDROXYLASE INHIBITORS | Smithkline Beecham Corporation (US) | 2009-12-02 | — | — | EP | claimed |
| WO-2008089052-A2 | N-SUBSTITUTED GLYCINE DERIVATIVES: HYDROXYLASE INHIBITORS | SMITHKLINE BEECHAM CORPORATION (US) | 2008-07-24 | — | — | WO | claimed |