Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGLN3 | Q9H6Z9 | 3/20 | 0.48 |
| ▸ | FEN1 | P39748 | 1/20 | 0.47 |
| ▸ | SLC13A5 | Q86YT5 | 1/20 | 0.42 |
| ▸ | EGLN1 | Q9GZT9 | 10/20 | 0.40 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.36 |
| ▸ | APLNR | P35414 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4371854 | 0.87 | EGLN3 (0.54) | EGLN3EGLN1HIF1A | |
| SCHEMBL3847099 | 0.86 | EGLN3 (0.49) | EGLN3FEN1SLC13A5EGLN1HIF1A | |
| SCHEMBL4359883 | 0.83 | EGLN3 (0.45) | EGLN3EGLN1 | |
| SCHEMBL4359069 | 0.82 | EGLN3 (0.51) | EGLN3EGLN1HIF1A | |
| SCHEMBL4357034 | 0.82 | EGLN3 (0.49) | EGLN3SLC13A5EGLN1HIF1A | |
| SCHEMBL4359892 | 0.81 | EGLN3 (0.59) | EGLN3EGLN1 | |
| SCHEMBL4362443 | 0.81 | EGLN3 (0.52) | EGLN3EGLN1 | |
| SCHEMBL4363082 | 0.80 | EGLN3 (0.51) | EGLN3EGLN1 | |
| SCHEMBL4359785 | 0.79 | EGLN3 (0.68) | EGLN3EGLN1 | |
| SCHEMBL4365361 | 0.78 | EGLN3 (0.42) | EGLN3EGLN1HIF1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2124565-A2 | N-SUBSTITUTED GLYCINE DERIVATIVES: HYDROXYLASE INHIBITORS | Smithkline Beecham Corporation (US) | 2009-12-02 | — | — | EP | claimed |
| WO-2008089052-A2 | N-SUBSTITUTED GLYCINE DERIVATIVES: HYDROXYLASE INHIBITORS | SMITHKLINE BEECHAM CORPORATION (US) | 2008-07-24 | — | — | WO | claimed |