Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGA4 | P13612 | 8/20 | 0.33 |
| ▸ | APP | P05067 | 4/20 | 0.33 |
| ▸ | ITGB1 | P05556 | 4/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
| ▸ | EIF4A1 | P60842 | 1/20 | 0.30 |
| ▸ | SLC6A1 | P30531 | 2/20 | 0.30 |
| ▸ | SLC6A11 | P48066 | 1/20 | 0.30 |
| ▸ | TYMP | P19971 | 1/20 | 0.30 |
| ▸ | UBE2I | P63279 | 1/20 | 0.30 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.30 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.30 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.30 |
| ▸ | SAE1 | Q9UBE0 | 1/20 | 0.30 |
| ▸ | UBA2 | Q9UBT2 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4017592 | 0.89 | KDM4E (0.34) | ITGA4APPNPC1RAB9ASLC6A1 | |
| SCHEMBL4359990 | 0.85 | APP (0.31) | ITGA4APPITGB1EIF4A1 | |
| SCHEMBL4363055 | 0.84 | APP (0.37) | APPSLC6A1SLC6A11TYMP | |
| SCHEMBL4363054 | 0.78 | APP (0.37) | APPNPC1RAB9ASLC6A1SLC6A11 | |
| SCHEMBL13669347 | 0.75 | KMT2A (0.36) | APPNPC1RAB9A | |
| SCHEMBL4017596 | 0.74 | KDM4E (0.31) | APPNPC1RAB9A | |
| SCHEMBL4367019 | 0.74 | — | — | |
| SCHEMBL4367051 | 0.73 | — | — | |
| SCHEMBL13669326 | 0.73 | SLC6A11 (0.37) | ITGA4NPC1RAB9APOLBSLC6A1 | |
| SCHEMBL13669342 | 0.72 | APP (0.40) | APPRAB9APOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8569516-B2 | Compounds and methods for fluorescent labeling | ELITECH HOLDING B.V. (NL) | 2013-10-29 | — | — | US | disclosed |
| US-7601851-B2 | Compounds and methods for fluorescent labeling | EPOCH BIOSCIENCES, INC. (US) | 2009-10-13 | — | — | US | disclosed |
| US-20060204990-A1 | Compounds and methods for fluorescent labeling | EPOCH BIOSCIENCES, INC. (US) | 2006-09-14 | — | — | US | disclosed |
| US-20050277144-A1 | Compounds and methods for fluorescent labeling | EPOCH BIOSCIENCES, INC. (US) | 2005-12-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060204990-A1 | Compounds and methods for fluorescent labeling | GLB1, HLCS, PFAS | ITGA4 2342/4885APP 3147/4885ITGB1 1711/4885 |
| US-20050277144-A1 | Compounds and methods for fluorescent labeling | HLCS, GLB1, TUBB | ITGA4 1747/4885APP 3054/4885ITGB1 1336/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.