SCHEMBL4360183

SCHEMBL4360183

O=C1NC(=S)SC1N=C=S

nearest known ligand 0.41

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
PSMD14 O00487 1/20 0.41
CA2 P00918 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4608931 0.64 APLNR (0.33)
SCHEMBL18722049 0.63
SCHEMBL3069828 0.63
SCHEMBL6592142 0.63
SCHEMBL5071842 0.63
SCHEMBL3085717 0.59 MAPT (0.48) PSMD14CA2
SCHEMBL4594922 0.58 ALDH1A1 (0.41)
SCHEMBL3072014 0.58
SCHEMBL6593214 0.58 PSMD14 (0.44) PSMD14CA2
SCHEMBL13165522 0.58 PSMD14 (0.48) PSMD14CA2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2134642-A1 IN VIVO TUMOR TARGETING AND SPECTROSCOPIC DETECTION WITH SURFACE-ENHANCED RAMAN NANOPARTICLE TAGS Emory University (US) 2009-12-23 EP claimed
WO-2008122035-A1 IN VIVO TUMOR TARGETING AND SPECTROSCOPIC DETECTION WITH SURFACE-ENHANCED RAMAN NANOPARTICLE TAGS EMORY UNIVERSITY (US) 2008-10-09 WO claimed
EP-1660320-A2 SURFACE ENHANCED RAMAN SPECTROSCOPY (SERS)-ACTIVE COMPOSITE NANOPARTICLES METHODS OF FABRICATION THEREOF AND METHODS OF USE THEREOF Emory University (US) 2006-05-31 EP claimed
WO-2005062741-A2 SURFACE ENHANCED RAMAN SPECTROSCOPY (SERS)-ACTIVE COMPOSITE NANOPARTICLES METHODS OF FABRICATION THEREOF AND METHODS OF USE THEREOF EMORY UNIVERSITY (US) 2005-07-14 WO claimed
US-8873038-B2 Tailored raman spectrocopic probes for ultrasensitive and highly multiplexed assays THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS (US) 2014-10-28 US disclosed
EP-2694686-A2 COMPOSITION AND METHODS RELATED TO MODIFICATION OF 5-METHYLCYTOSINE (5mC) The University of Chicago (US) 2014-02-12 EP disclosed
WO-2012138973-A2 COMPOSITION AND METHODS RELATED TO MODIFICATION OF 5-METHYLCYTOSINE (5mC) THE UNIVERSITY OF CHICAGO (US) 2012-10-11 WO disclosed
US-20120212733-A1 TAILORED RAMAN SPECTROCOPIC PROBES FOR ULTRASENSITIVE AND HIGHLY MULTIPLEXED ASSAYS THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS 2012-08-23 US disclosed
EP-2134642-A1 IN VIVO TUMOR TARGETING AND SPECTROSCOPIC DETECTION WITH SURFACE-ENHANCED RAMAN NANOPARTICLE TAGS Emory University (US) 2009-12-23 EP disclosed
WO-2008122035-A1 IN VIVO TUMOR TARGETING AND SPECTROSCOPIC DETECTION WITH SURFACE-ENHANCED RAMAN NANOPARTICLE TAGS EMORY UNIVERSITY (US) 2008-10-09 WO disclosed
US-20050227231-A1 Device for sequencing nucleic acid molecules TCHERKASSOV DIMITRI 2005-10-13 US disclosed