Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | GLA | P06280 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | F2 | P00734 | 1/20 | 0.30 |
| ▸ | ELANE | P08246 | 1/20 | 0.30 |
| ▸ | CTSG | P08311 | 1/20 | 0.30 |
| ▸ | CTRC | Q99895 | 1/20 | 0.30 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.30 |
| ▸ | CRHBP | P24387 | 1/20 | 0.30 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1264768 | 0.69 | ALDH1A1 (0.46) | ALDH1A1MEN1KMT2ASMN1; SMN2KDM4E | |
| SCHEMBL11393459 | 0.66 | ALDH1A1 (0.61) | ALDH1A1MEN1KMT2ASMN1; SMN2KDM4E | |
| SCHEMBL4360183 | 0.58 | PSMD14 (0.41) | — | |
| SCHEMBL13871460 | 0.56 | F2 (0.42) | ALDH1A1MEN1KMT2ASMN1; SMN2KDM4E | |
| Isothiocyanate SCHEMBL4594925 | 0.55 | GSK3A (0.50) | ALDH1A1MEN1KMT2AGAA | |
| SCHEMBL5915574 | 0.55 | ALDH1A1 (0.40) | ALDH1A1MEN1KMT2ASMN1; SMN2KDM4E | |
| SCHEMBL28492345 | 0.55 | ALDH1A1 (0.51) | ALDH1A1MEN1KMT2ASMN1; SMN2KDM4E | |
| SCHEMBL13074585 | 0.54 | ALDH1A1 (0.46) | ALDH1A1MEN1KMT2ASMN1; SMN2KDM4E | |
| SCHEMBL1361452 | 0.53 | F2 (0.39) | ALDH1A1MEN1KMT2ASMN1; SMN2KDM4E | |
| SCHEMBL153669 | 0.53 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1497650-A4 | A METHOD FOR DETECTING LYSOSOMAL STORAGE DISEASES | SEIKAGAKU KOGYO CO LTD (JP) | 2008-04-02 | — | — | EP | disclosed |
| EP-1497650-A2 | A METHOD FOR DETECTING LYSOSOMAL STORAGE DISEASES | SEIKAGAKU CORPORATION (JP) | 2005-01-19 | — | — | EP | disclosed |
| WO-2003092601-A2 | A METHOD FOR DETECTING LYSOSOMAL STORAGE DISEASES | SEIKAGAKU CORPORATION (JP) | 2003-11-13 | — | — | WO | disclosed |
| WO-1993015406-A1 | METHODS AND APPARATUS FOR ASSAY OF SULPHATED POLYSACCHARIDES | IMPERIAL COLLEGE OF SCIENCE, TECHNOLOGY & MEDECINE (GB) | 1993-08-05 | — | — | WO | disclosed |