Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C19 | P33261 | 3/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.44 |
| ▸ | MAPT | P10636 | 3/20 | 0.43 |
| ▸ | LMNA | P02545 | 3/20 | 0.42 |
| ▸ | CNR1 | P21554 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | CPA1 | P15085 | 3/20 | 0.41 |
| ▸ | POLB | P06746 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | NSD2 | O96028 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | BRD4 | O60885 | 1/20 | 0.39 |
| ▸ | GABBR2 | O75899 | 2/20 | 0.38 |
| ▸ | GABBR1 | Q9UBS5 | 2/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4360490 | 1.00 | CYP2C19 (0.46) | CYP2C19KMT2ACYP2D6CYP2C9MEN1 | |
| SCHEMBL5244764 | 0.87 | ALDH1A1 (0.58) | CYP2C19KMT2ACYP2D6CYP2C9MEN1 | |
| SCHEMBL16683403 | 0.86 | BRD4 (0.53) | CYP2C19KMT2ACYP2D6CYP2C9MEN1 | |
| SCHEMBL4120421 | 0.86 | BRD4 (0.53) | CYP2C19KMT2ACYP2D6CYP2C9MEN1 | |
| SCHEMBL22831446 | 0.85 | LMNA (0.46) | CYP2C19KMT2ACYP2D6CYP2C9ALDH1A1 | |
| SCHEMBL220114 | 0.85 | CNR1 (0.43) | CYP2C19KMT2ACYP2D6CYP2C9MEN1 | |
| SCHEMBL220113 | 0.85 | CNR1 (0.43) | CYP2C19KMT2ACYP2D6CYP2C9MEN1 | |
| SCHEMBL22831433 | 0.85 | CPA1 (0.51) | CYP2C19CYP2D6ALDH1A1MAPTLMNA | |
| SCHEMBL22831457 | 0.84 | ALDH1A1 (0.47) | CYP2C19KMT2AMEN1ALDH1A1MAPT | |
| SCHEMBL22831459 | 0.84 | ALDH1A1 (0.44) | CYP2C19KMT2AMEN1ALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8293926-B2 | Method of producing optically active 4-amino-3-substituted phenylbutanoic acid | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2012-10-23 | — | — | US | disclosed |
| US-20090137819-A1 | Method of Producing Optically Active 4-Amino-3-Substituted Phenylbutanoic Acid | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2009-05-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090137819-A1 | Method of Producing Optically Active 4-Amino-3-Substituted Phenylbutanoic Acid | ALAD, ATP6V1B1, DAO | CYP2C19 644/4885KMT2A 2677/4885CYP2D6 493/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.