Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | PIK3CG | P48736 | 3/20 | 0.34 |
| ▸ | DHFR | P00374 | 3/20 | 0.33 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.32 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.32 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.32 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.30 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25899100 | 0.80 | HSD17B10 (0.39) | HSD17B10PIK3CGDHFRPIK3CAPIK3CB | |
| SCHEMBL4361085 | 0.79 | HSD17B10 (0.48) | HSD17B10PIK3CGDHFRPIK3CAPIK3CB | |
| SCHEMBL11628253 | 0.77 | PIK3CG (0.35) | HSD17B10PIK3CGDHFRPIK3CAPIK3CB | |
| SCHEMBL24629319 | 0.74 | PIK3CG (0.42) | PIK3CGDHFRPIK3CAPIK3CBHDAC6 | |
| SCHEMBL11301495 | 0.74 | HSD17B10 (0.38) | HSD17B10PIK3CGDHFRPIK3CAPIK3CB | |
| SCHEMBL6239850 | 0.72 | PIK3CG (0.41) | PIK3CGDHFRPIK3CAPIK3CBHDAC6 | |
| Xanthopterin SCHEMBL906220 | 0.71 | PIK3CG (0.46) | PIK3CGDHFRPIK3CAPIK3CBHDAC6 | |
| Pterin-6-Carboxylic Acid SCHEMBL31438602 | 0.71 | DHFR (0.45) | HSD17B10PIK3CGDHFRPIK3CAPIK3CB | |
| Pterin-6-Carboxylic Acid SCHEMBL13820952 | 0.71 | DHFR (0.45) | HSD17B10PIK3CGDHFRPIK3CAPIK3CB | |
| Xanthopterin SCHEMBL6475885 | 0.70 | PIK3CG (0.45) | PIK3CGDHFRPIK3CAPIK3CBHDAC6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0318926-B1 | Intermediates for synthesizing 5,6,7,8-tetrahydro-L-erythro-biopterin and its derivatives | VITAMIN KENKYUSHO KK (JP) | 1995-05-03 | — | — | EP | claimed |
| EP-0318926-A2 | Intermediates for synthesizing 5,6,7,8-tetrahydro-L-erythro-biopterin and its derivatives | Kabushiki Kaisha Vitamin Kenkyusyo (JP) | 1989-06-07 | — | — | EP | claimed |
| JP-1320993-A | — | — | None | — | — | JP | disclosed |
| EP-0318926-B1 | Intermediates for synthesizing 5,6,7,8-tetrahydro-L-erythro-biopterin and its derivatives | VITAMIN KENKYUSHO KK (JP) | 1995-05-03 | — | — | EP | disclosed |
| US-5037981-A | Intermediates for synthesizing BH4 and its derivatives | KABUSHIKI KAISHA VITAMIN KENKYUSO (JP) | 1991-08-06 | — | — | US | disclosed |
| US-4937342-A | Intermediates for synthesizing BH4 and its derivatives | KABUSHIKI KAISHA VITAMIN KENKYUSYO (JP) | 1990-06-26 | — | — | US | disclosed |
| JP-H01320993-A | PRODUCTION OF L-BIOPTERIN | BITAMIN KENKYUSHO:KK | 1989-12-27 | — | — | JP | disclosed |
| EP-0318926-A2 | Intermediates for synthesizing 5,6,7,8-tetrahydro-L-erythro-biopterin and its derivatives | Kabushiki Kaisha Vitamin Kenkyusyo (JP) | 1989-06-07 | — | — | EP | disclosed |