Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TOP2B | Q02880 | 1/20 | 0.38 |
| ▸ | FLT3 | P36888 | 2/20 | 0.37 |
| ▸ | GSR | P00390 | 2/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | MALT1 | Q9UDY8 | 1/20 | 0.36 |
| ▸ | PIM1 | P11309 | 1/20 | 0.35 |
| ▸ | PIM3 | Q86V86 | 1/20 | 0.35 |
| ▸ | PIM2 | Q9P1W9 | 1/20 | 0.35 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.34 |
| ▸ | MAPK9 | P45984 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | CA12 | O43570 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | CA9 | Q16790 | 1/20 | 0.33 |
| ▸ | PDE5A | O76074 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1355114 | 0.82 | ALDH1A1 (0.35) | MAPK8MAPK9ALDH1A1CYP2C19 | |
| SCHEMBL4350048 | 0.78 | KAT2B (0.32) | ALDH1A1 | |
| SCHEMBL1355590 | 0.75 | DRD2 (0.40) | NPSR1 | |
| SCHEMBL1355874 | 0.74 | SIGMAR1 (0.41) | NPSR1TSHR | |
| SCHEMBL1356124 | 0.72 | ALDH1A1 (0.46) | MALT1ALDH1A1CYP2C19 | |
| SCHEMBL13589541 | 0.71 | GSR (0.50) | TOP2BFLT3GSRNPSR1TSHR | |
| SCHEMBL4360471 | 0.71 | GSR (0.37) | GSRALDH1A1 | |
| SCHEMBL3122170 | 0.69 | CYP2C19 (0.46) | MALT1CYP2C19 | |
| SCHEMBL941266 | 0.68 | G6PD (0.37) | ALDH1A1 | |
| SCHEMBL10485251 | 0.68 | ALDH1A1 (0.67) | NPSR1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009150144-A1 | NEW GPR119MODULATORS | INOVACIA AB (SE) | 2009-12-17 | — | — | WO | disclosed |