SCHEMBL436281

SCHEMBL436281

O=C(O)C(O)C(O)C(O)C(O)C(O)CCCCCCCCCCCCO

nearest known ligand 0.55

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
PDE4A P27815 1/20 0.55
TSHR P16473 2/20 0.41
CYP2C9 P11712 1/20 0.41
LMNA P02545 1/20 0.38
GPR84 Q9NQS5 4/20 0.35
FFAR1 O14842 2/20 0.35
FFAR4 Q5NUL3 1/20 0.35
PTPN1 P18031 2/20 0.35
USP2 O75604 1/20 0.34
SLCO1B1 Q9Y6L6 1/20 0.34
ALDH1A1 P00352 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17889062 1.00 PDE4A (0.55) PDE4ATSHRCYP2C9LMNAGPR84
SCHEMBL5168154 1.00 PDE4A (0.55) PDE4ATSHRCYP2C9LMNAGPR84
SCHEMBL28496980 1.00 PDE4A (0.55) PDE4ATSHRCYP2C9LMNAGPR84
SCHEMBL28380507 1.00 PDE4A (0.55) PDE4ATSHRCYP2C9LMNAGPR84
SCHEMBL28474333 0.98 PDE4A (0.53) PDE4ATSHRCYP2C9LMNAGPR84
SCHEMBL29006932 0.98 PDE4A (0.53) PDE4ATSHRCYP2C9LMNAGPR84
SCHEMBL28832081 0.98 PDE4A (0.53) PDE4ATSHRCYP2C9LMNAGPR84
SCHEMBL28426162 0.98 PDE4A (0.53) PDE4ATSHRCYP2C9LMNAGPR84
SCHEMBL28465166 0.98 PDE4A (0.53) PDE4ATSHRCYP2C9LMNAGPR84
SCHEMBL29207127 0.98 PDE4A (0.53) PDE4ATSHRCYP2C9LMNAGPR84

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 170 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4452200-A1 COSMETIC COMPOSITION COMPRISING A NATURAL RESIN L'OREAL (FR) 2024-10-30 EP claimed
EP-4362882-A1 SOLIDIFIED LIP GLOSS STICK-TYPE COSMETIC COMPOSITION STABILIZING HIGH-CONTENT OLIGOMER-TYPE PHYTOSTEROL ESTERS C&C International Co., Ltd. (KR) 2024-05-08 EP claimed
US-20240016725-A1 SOLIDIFIED LIP GLOSS STICK-TYPE COSMETIC COMPOSITION STABILIZING HIGH-CONTENT OLIGOMER-TYPE PHYTOSTEROL ESTERS C&C INTERNATIONAL CO., LTD. (KR) 2024-01-18 US claimed
WO-2023163457-A1 METHOD FOR PREPARING COMPOSITE POWDER SURFACE TREATED WITH NATURALLY DERIVED RESIN AND COSMETIC COMPOSITION CONTAINING COMPOSITE POWDER PREPARED THEREBY 주식회사 코스메카코리아 2023-08-31 WO claimed
WO-2023118430-A1 COSMETIC COMPOSITION COMPRISING A NATURAL RESIN L'OREAL (FR) 2023-06-29 WO claimed
WO-2023054797-A1 WATER-IN-OIL SOLID COSMETIC COMPOSITION HAVING APPROPRIATE RATIO OF AQUEOUS PHASE AND OIL PHASE 코스맥스 주식회사 2023-04-06 WO claimed
WO-2023277258-A1 SOLIDIFIED LIP GLOSS STICK-TYPE COSMETIC COMPOSITION STABILIZING HIGH-CONTENT OLIGOMER-TYPE PHYTOSTEROL ESTERS C&C INTERNATIONAL CO., LTD. (KR) 2023-01-05 WO claimed
CN-111050732-A Cosmetic composition and method for preparing the same 株式会社爱茉莉太平洋 2020-04-21 CN claimed
CN-109223588-A A kind of replenishing water and preserving moisture cosmetics 安婕妤化妆品科技股份有限公司 2019-01-18 CN claimed
CN-108014026-A Rich lip composition and its rich lip lipstick 广州智媛生物科技有限公司 2018-05-11 CN claimed
WO-2006085907-A2 SANITIZING COMPOSITION AND METHOD OF PREPARATION BROWN STEVEN J (US) 2006-08-17 WO claimed
US-20050271595-A1 Sanitizing composition and method of preparation BROWN JAMES S 2005-12-08 US claimed
US-6887494-B2 Pigments and extender pigments with enhanced skin adhesion for cosmetic preparations US COSMETICS (US) 2005-05-03 US claimed
US-6869597-B2 Cosmetic care or makeup composition for a keratin material comprising at least one photoprotective agent and at least one ester comprising an aromatic group L'OREAL S.A. (FR) 2005-03-22 US claimed
US-20040241121-A1 Cosmetic composition comprising at least one polyester resulting from esterification of at least one triglyceride of hydroxylated carboxylic acid(s) and also comprising at least one pasty compound L'OREAL S.A. (FR) 2004-12-02 US claimed
US-20040241198-A1 Cosmetic composition comprising at least one polyester resulting from esterification of at least one triglyceride of hydroxylated carboxylic acid(s) and at least one oil with a molar mass of 650 to 10 000 g/mol L'OREAL S.A. (FR) 2004-12-02 US claimed
US-20040166130-A1 Lanolin-free cosmetic composition comprising a hydroxylated fatty acid aromatic ester L'OREAL (FR) 2004-08-26 US claimed
US-20030077234-A1 Cosmetic care or makeup composition for a keratin material comprising at least one photoprotective agent and at least one ester comprising an aromatic group L'OREAL. 2003-04-24 US claimed
US-20020155962-A1 Nonaqueous hair styling composition and method of use ANDREW JERGENS COMPANY, THE 2002-10-24 US claimed
US-20020039562-A1 Pigments and extender pigments with enhanced skin adhesion for cosmetic preparations KOBAYASHI MASARU (US) 2002-04-04 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20040241198-A1 Cosmetic composition comprising at least one polyester resulting from esterification of at least one triglyceride of hydroxylated carboxylic acid(s) and at least one oil with a molar mass of 650 to 10 000 g/mol FABP4, KRT18, PPARG PDE4A 4482/4885TSHR 1444/4885CYP2C9 1765/4885
US-20040166130-A1 Lanolin-free cosmetic composition comprising a hydroxylated fatty acid aromatic ester CYP51A1, ELOVL3, ELOVL5 PDE4A 1746/4885TSHR 4731/4885CYP2C9 994/4885
US-20040241121-A1 Cosmetic composition comprising at least one polyester resulting from esterification of at least one triglyceride of hydroxylated carboxylic acid(s) and also comprising at least one pasty compound KRT18, CUTA, CETP PDE4A 3567/4885TSHR 2664/4885CYP2C9 1536/4885
US-20030077234-A1 Cosmetic care or makeup composition for a keratin material comprising at least one photoprotective agent and at least one ester comprising an aromatic group KRT18, CUTA, TYR PDE4A 4443/4885TSHR 2942/4885CYP2C9 1522/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.