SCHEMBL5168154

SCHEMBL5168154

O=C(O)C(O)C(O)C(O)C(O)C(O)C(O)C(O)CCCCCCCCCCO

nearest known ligand 0.55

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
PDE4A P27815 1/20 0.55
TSHR P16473 2/20 0.41
CYP2C9 P11712 1/20 0.41
LMNA P02545 1/20 0.38
GPR84 Q9NQS5 4/20 0.35
FFAR1 O14842 2/20 0.35
FFAR4 Q5NUL3 1/20 0.35
PTPN1 P18031 2/20 0.35
USP2 O75604 1/20 0.34
SLCO1B1 Q9Y6L6 1/20 0.34
ALDH1A1 P00352 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17889062 1.00 PDE4A (0.55) PDE4ATSHRCYP2C9LMNAGPR84
SCHEMBL28496980 1.00 PDE4A (0.55) PDE4ATSHRCYP2C9LMNAGPR84
SCHEMBL28380507 1.00 PDE4A (0.55) PDE4ATSHRCYP2C9LMNAGPR84
SCHEMBL436281 1.00 PDE4A (0.55) PDE4ATSHRCYP2C9LMNAGPR84
SCHEMBL28474333 0.98 PDE4A (0.53) PDE4ATSHRCYP2C9LMNAGPR84
SCHEMBL29006932 0.98 PDE4A (0.53) PDE4ATSHRCYP2C9LMNAGPR84
SCHEMBL28832081 0.98 PDE4A (0.53) PDE4ATSHRCYP2C9LMNAGPR84
SCHEMBL28426162 0.98 PDE4A (0.53) PDE4ATSHRCYP2C9LMNAGPR84
SCHEMBL28465166 0.98 PDE4A (0.53) PDE4ATSHRCYP2C9LMNAGPR84
SCHEMBL29207127 0.98 PDE4A (0.53) PDE4ATSHRCYP2C9LMNAGPR84

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1457201-B1 Cosmetic composition containing a polyester of a hydrocarboxylated carboxylic acid triglyceride and an oil with a molar mass from 650 to 1000 g/ml OREAL (FR) 2007-04-11 EP claimed
US-6869597-B2 Cosmetic care or makeup composition for a keratin material comprising at least one photoprotective agent and at least one ester comprising an aromatic group L'OREAL S.A. (FR) 2005-03-22 US claimed
US-20040241121-A1 Cosmetic composition comprising at least one polyester resulting from esterification of at least one triglyceride of hydroxylated carboxylic acid(s) and also comprising at least one pasty compound L'OREAL S.A. (FR) 2004-12-02 US claimed
US-20040241198-A1 Cosmetic composition comprising at least one polyester resulting from esterification of at least one triglyceride of hydroxylated carboxylic acid(s) and at least one oil with a molar mass of 650 to 10 000 g/mol L'OREAL S.A. (FR) 2004-12-02 US claimed
US-20040166130-A1 Lanolin-free cosmetic composition comprising a hydroxylated fatty acid aromatic ester L'OREAL (FR) 2004-08-26 US claimed
US-20030077234-A1 Cosmetic care or makeup composition for a keratin material comprising at least one photoprotective agent and at least one ester comprising an aromatic group L'OREAL. 2003-04-24 US claimed
CN-104877179-B A kind of organic composite heat stabilizer and preparation method thereof 杭州鸿雁管道系统科技有限公司 2018-02-23 CN disclosed
CN-104877252-B A kind of unleaded low toxicity polyvinyl chloride composite materials and preparation method thereof 杭州鸿雁管道系统科技有限公司 2017-06-06 CN disclosed
CN-104877251-B A kind of environmentally friendly low cigarette leadless polyvinyl chloride electrician pipe and preparation method thereof 杭州鸿雁电器有限公司 2017-06-06 CN disclosed
CN-104877252-A Lead-free and low-toxicity polyvinyl chloride composite material and preparation method thereof HANGZHOU HONGYAN PIPELINE SYSTEM SCIENCE & TECHNOLOGY CO LTD 2015-09-02 CN disclosed
CN-104403760-A Lubricating grease specially used for reducer case and preparation method thereof Xinxiang hengxing chemical industry co ltd 2015-03-11 CN disclosed
US-7250159-B1 Compositions comprising at least one ester of at least one hydroxylated aliphatic compound L'ORéAL S.A. (FR) 2007-07-31 US disclosed
US-6893648-B2 Composition and method for treatment of vaginal dryness MERMELSTEIN HAROLD (US) 2005-05-17 US disclosed
US-6869597-B2 Cosmetic care or makeup composition for a keratin material comprising at least one photoprotective agent and at least one ester comprising an aromatic group L'OREAL S.A. (FR) 2005-03-22 US disclosed
US-20040241121-A1 Cosmetic composition comprising at least one polyester resulting from esterification of at least one triglyceride of hydroxylated carboxylic acid(s) and also comprising at least one pasty compound L'OREAL S.A. (FR) 2004-12-02 US disclosed
US-20040241198-A1 Cosmetic composition comprising at least one polyester resulting from esterification of at least one triglyceride of hydroxylated carboxylic acid(s) and at least one oil with a molar mass of 650 to 10 000 g/mol L'OREAL S.A. (FR) 2004-12-02 US disclosed
US-20040166130-A1 Lanolin-free cosmetic composition comprising a hydroxylated fatty acid aromatic ester L'OREAL (FR) 2004-08-26 US disclosed
US-20030077234-A1 Cosmetic care or makeup composition for a keratin material comprising at least one photoprotective agent and at least one ester comprising an aromatic group L'OREAL. 2003-04-24 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20040241198-A1 Cosmetic composition comprising at least one polyester resulting from esterification of at least one triglyceride of hydroxylated carboxylic acid(s) and at least one oil with a molar mass of 650 to 10 000 g/mol FABP4, KRT18, PPARG PDE4A 4482/4885TSHR 1444/4885CYP2C9 1765/4885
US-20040166130-A1 Lanolin-free cosmetic composition comprising a hydroxylated fatty acid aromatic ester CYP51A1, ELOVL3, ELOVL5 PDE4A 1746/4885TSHR 4731/4885CYP2C9 994/4885
US-20040241121-A1 Cosmetic composition comprising at least one polyester resulting from esterification of at least one triglyceride of hydroxylated carboxylic acid(s) and also comprising at least one pasty compound KRT18, CUTA, CETP PDE4A 3567/4885TSHR 2664/4885CYP2C9 1536/4885
US-20030077234-A1 Cosmetic care or makeup composition for a keratin material comprising at least one photoprotective agent and at least one ester comprising an aromatic group KRT18, CUTA, TYR PDE4A 4443/4885TSHR 2942/4885CYP2C9 1522/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.