SCHEMBL4363597

SCHEMBL4363597

O=C(Cl)c1cccc(N2C(=O)C=CC2=O)c1

nearest known ligand 0.72

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MGLL Q99685 10/20 0.62
FAAH O00519 4/20 0.62
HSP90AA1 P07900 4/20 0.55
MAPT P10636 3/20 0.55
MEN1 O00255 1/20 0.55
CYP1A2 P05177 1/20 0.55
CYP3A4 P08684 1/20 0.55
CYP2C9 P11712 1/20 0.55
CYP2C19 P33261 1/20 0.55
KMT2A Q03164 1/20 0.55
APOBEC3G Q9HC16 1/20 0.55
ALDH1A1 P00352 3/20 0.51
HTT P42858 3/20 0.51
PKM P14618 2/20 0.51
ATM Q13315 1/20 0.51
NSD2 O96028 1/20 0.50
G6PD P11413 1/20 0.50
KEAP1 Q14145 1/20 0.50
NFE2L2 Q16236 1/20 0.50
HPN P05981 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8530013 0.85 MGLL (0.67) MGLLFAAHHSP90AA1MAPTMEN1
SCHEMBL522308 0.84 NSD2 (0.67) MGLLFAAHHSP90AA1MAPTMEN1
SCHEMBL10515423 0.84 PARP1 (0.65) MGLLFAAHHSP90AA1MAPTMEN1
SCHEMBL32670837 0.84 NSD2 (0.67) MGLLFAAHHSP90AA1MAPTMEN1
SCHEMBL11023896 0.84 MGLL (0.64) MGLLFAAHHSP90AA1MAPTMEN1
SCHEMBL29510746 0.84 PARP1 (0.65) MGLLFAAHHSP90AA1MAPTMEN1
SCHEMBL24529797 0.82 MGLL (0.62) MGLLFAAHHSP90AA1MAPTMEN1
SCHEMBL4594492 0.82 MGLL (0.62) MGLLFAAHHSP90AA1MAPTMEN1
Hydrochloric Acid SCHEMBL4956408 0.82 NSD2 (0.65) MGLLFAAHHSP90AA1MAPTMEN1
SCHEMBL29510515 0.82 MGLL (0.62) MGLLFAAHHSP90AA1MAPTMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117987061-A Photo-curing adhesive for bonding flexible printed circuit board and preparation method thereof 青岛德聚胶接技术有限公司 2024-05-07 CN claimed
JP-62252455-A None JP disclosed
CN-117987061-B Photo-curing adhesive for bonding flexible printed circuit board and preparation method thereof 青岛德聚胶接技术有限公司 2024-10-11 CN disclosed
CN-117987061-A Photo-curing adhesive for bonding flexible printed circuit board and preparation method thereof 青岛德聚胶接技术有限公司 2024-05-07 CN disclosed
US-20090162290-A1 METHOD FOR THE SYNTHESIS OF PENTA-PENDANT ENANTIOMER-PURE CHELATORS AND PROCESS FOR THERAPEUTICALLY ACTIVE BIOCONJUGATES PREPARATION BY A COVALENT BINDING THEREOF THERAPHARM GMBH 2009-06-25 US disclosed
EP-1942949-A1 METHOD FOR THE SYNTHESIS OF PENTAPENDANT ENANTIOMER-PURE CHELATORS AND PROCESS FOR THERAPEUTICALLY ACTIVE BIO-CONJUGATES PREPARATION BY A COVALENT BINDING OF THEREOF Therapharm GmbH (CH) 2008-07-16 EP disclosed
US-7344699-B2 Drug conjugate comprising an erythropoietin receptor ligand and an anticancer agent THE QUEEN'S UNIVERSITY OF BELFAST (GB) 2008-03-18 US disclosed
WO-2007028639-A1 METHOD FOR THE SYNTHESIS OF PENTAPENDANT ENANTIOMER-PURE CHELATORS AND PROCESS FOR THERAPEUTICALLY ACTIVE BIO-CONJUGATES PREPARATION BY A COVALENT BINDING OF THEREOF THERAPHARM GMBH (CH) 2007-03-15 WO disclosed
US-20060057063-A1 Medicaments THE QUEEN'S UNIVERSITY OF BELFAST (GB) 2006-03-16 US disclosed
EP-1526866-A2 DRUG CONJUGATE COMPRISING AN ERYTHROPOIETIN RECEPTOR LIGAND AND AN ANTICANCER AGENT The Queen's University of Belfast (GB) 2005-05-04 EP disclosed
WO-2003097106-A2 DRUG CONJUGATE COMPRISING AN ERYTHROPOIETIN RECEPTOR LIGAND AND AN ANTICANCER AGENT THE QUEEN'S UNIVERSITY OF BELFAST (GB) 2003-11-27 WO disclosed
US-6329531-B1 FOR THERAPY OF ALZHEIMER'S DISEASE SCHERING AG (DE) 2001-12-11 US disclosed
US-4851494-A MOLDING, COATING CIBA-GEIGY CORPORATION (US) 1989-07-25 US disclosed
EP-0300970-A1 Curable polyether amides CIBA-GEIGY AG (CH) 1989-01-25 EP disclosed
JP-S62252455-A POLYAMIDE BISMALEIMIDE RESIN COMPOSITION YOBEA RULON KOGYO KK 1987-11-04 JP disclosed
US-4629689-A Binding assay with amplified read-out and gas-phase detection ALLIED CORPORATION (US) 1986-12-16 US disclosed
EP-0173055-A2 Binding assay with amplified read-out and gas-phase detection ALLIED CORPORATION (US) 1986-03-05 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090162290-A1 METHOD FOR THE SYNTHESIS OF PENTA-PENDANT ENANTIOMER-PURE CHELATORS AND PROCESS FOR THERAPEUTICALLY ACTIVE BIOCONJUGATES PREPARATION BY A COVALENT BINDING THEREOF C5, C3AR1, SPR MGLL 4807/4885FAAH 4005/4885HSP90AA1 4337/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.