SCHEMBL522308

SCHEMBL522308

O=C(O)c1cccc(N2C(=O)C=CC2=O)c1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NSD2 O96028 1/20 0.67
G6PD P11413 1/20 0.67
KEAP1 Q14145 1/20 0.67
NFE2L2 Q16236 1/20 0.67
MGLL Q99685 8/20 0.64
FAAH O00519 4/20 0.64
DDAH1 O94760 1/20 0.61
L3MBTL1 Q9Y468 2/20 0.58
ALDH1A1 P00352 5/20 0.58
HSP90AA1 P07900 3/20 0.58
PKM P14618 1/20 0.58
HTT P42858 1/20 0.58
ATM Q13315 1/20 0.58
KMT2A Q03164 6/20 0.56
MEN1 O00255 5/20 0.54
KDM4E B2RXH2 3/20 0.54
GAA P10253 2/20 0.54
HSD17B10 Q99714 2/20 0.54
HPGD P15428 2/20 0.54
MAPT P10636 2/20 0.54

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL32670837 1.00 NSD2 (0.67) NSD2G6PDKEAP1NFE2L2MGLL
Hydrochloric Acid SCHEMBL4956408 0.98 NSD2 (0.65) NSD2G6PDKEAP1NFE2L2MGLL
Hydrazine SCHEMBL16912716 0.96 NSD2 (0.62) NSD2G6PDKEAP1NFE2L2MGLL
Alcohol SCHEMBL29133134 0.92 NSD2 (0.57) NSD2G6PDKEAP1NFE2L2MGLL
SCHEMBL8838907 0.92 NSD2 (0.57) NSD2G6PDKEAP1NFE2L2MGLL
SCHEMBL1548309 0.88 ALDH1A1 (0.54) NSD2G6PDKEAP1NFE2L2MGLL
SCHEMBL8530013 0.87 MGLL (0.67) NSD2G6PDKEAP1NFE2L2MGLL
SCHEMBL7799644 0.86 MGLL (0.60) NSD2G6PDKEAP1NFE2L2MGLL
SCHEMBL10515423 0.85 PARP1 (0.65) NSD2G6PDKEAP1NFE2L2MGLL
SCHEMBL29510746 0.85 PARP1 (0.65) NSD2G6PDKEAP1NFE2L2MGLL

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 603 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025091021-A1 POLYMERIZED ALBUMIN AND METHODS OF MAKING AND USING THEREOF OHIO STATE INNOVATION FOUNDATION (US) 2025-05-01 WO claimed
WO-2025091017-A1 SYNTHETIC WHOLE BLOOD SUBSTITUTES OHIO STATE INNOVATION FOUNDATION (US) 2025-05-01 WO claimed
EP-4251210-B1 MULTI-SPECIFIC HUMAN ALBUMIN NANOPARTICLES DECORATED WITH ANTIBODY FRAGMENTS AND LOADED WITH CYTOTOXICS ANBITION S R L (IT) 2025-03-19 EP claimed
EP-4251211-B1 USE OF MULTI-SPECIFIC HUMAN ALBUMIN NANOPARTICLES DECORATED WITH ANTIBODY FRAGMENTS AND LOADED WITH CYTOTOXIC DRUGS ANBITION S R L (IT) 2025-02-26 EP claimed
US-20240294609-A1 STABILIZED HEMOGLOBIN COMPOSITIONS AND PHARMACEUTICAL FORMULATIONS THEREOF GOLD BLAZE, LTD. (SG) 2024-09-05 US claimed
US-20240000967-A1 USE OF MULTI-SPECIFIC HUMAN ALBUMIN NANOPARTICLES DECORATED WITH ANTIBODY FRAGMENTS AND LOADED WITH CYTOTOXICS ANBITION S.R.L. (IT) 2024-01-04 US claimed
CN-117304811-A High-functionality vegetable oil-based UV (ultraviolet) light-cured resin as well as preparation method and application thereof 佛山科学技术学院 2023-12-29 CN claimed
US-20230414772-A1 MULTI-SPECIFIC HUMAN ALBUMIN NANOPARTICLES DECORATED WITH ANTIBODY FRAGMENTS AND LOADED WITH CYTOTOXICS ANBITION S.R.L. (IT) 2023-12-28 US claimed
CN-117165366-A Universal UV light-cured modified vegetable oil resin and synthetic method and application thereof 佛山科学技术学院 2023-12-05 CN claimed
CN-117042807-A Multispecific human albumin nanoparticles modified with antibody fragments and loaded with cytotoxic drugs 安必圣有限责任公司 2023-11-10 CN claimed
WO-2007083984-A1 CONJUGATE COMPRISING PHARMACEUTICAL ACTIVE COMPOUND COVALENTLY BOUND TO MUCOADHESIVE POLYMER AND TRANSMUCOSAL DELIVERY METHOD OF PHARMACEUTICAL ACTIVE COMPOUND USING THE SAME GWANGJU INSTITUTE OF SCIENCE AND TECHNOLOGY (KR) 2007-07-26 WO claimed
US-5466357-A THERMOPLASTIC MATRIX PREPREG COMPOSITE PRODUCT THE UNIVERSITY OF CONNECTICUT (US) 1995-11-14 US claimed
US-5232560-A Polymerizing at least one carboxy group containing monomer from aqueous solution onto electrically conductive filler material; thermally stable thermoplastic coatings; prepregs BELL JAMES P (US) 1993-08-03 US claimed
EP-0336856-B1 WITH MALEIMIDE GROUPS FUNCTIONALIZED AROMATIC POLYAMIDEIMIDES, PROCESS FOR THEIR PREPARATION AND THEIR USE FOR PREPARING CROSS-LINKED POLYMERS CIBA-GEIGY AG (CH) 1993-03-03 EP claimed
EP-0526587-A1 MODIFICATION OF POLYMER SURFACES BY TREATMENT WITH Ce(IV) SALTS AND ELECTROMAGNETIC RADIATION NOVO NORDISK A/S (DK) 1993-02-10 EP claimed
WO-1991016377-A1 MODIFICATION OF POLYMER SURFACES BY TREATMENT WITH Ce(IV) SALTS AND ELECTROMAGNETIC RADIATION NOVO NORDISK A/S (DK) 1991-10-31 WO claimed
EP-0198309-B1 METHOD FOR IMPROVING RUBBERS NIPPON ZEON CO., LTD. (JP) 1990-10-24 EP claimed
US-4927900-A Aromatic polyamidoimides having maleimido end groups RHONE-POULENC CHIMIE (FR) 1990-05-22 US claimed
US-4704427-A MODIFICATION WITH LEWIS ACID, CARBOXYLATION NIPPON ZEON CO., LTD. (JP) 1987-11-03 US claimed
EP-0227351-A2 Immobilized C-peptide antibody, and the preparation and use thereof SHIONOGI & CO., LTD. (JP) 1987-07-01 EP claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230414772-A1 MULTI-SPECIFIC HUMAN ALBUMIN NANOPARTICLES DECORATED WITH ANTIBODY FRAGMENTS AND LOADED WITH CYTOTOXICS ALB, ASNS, ENPEP NSD2 2675/4885G6PD 3594/4885KEAP1 3650/4885
US-20240000967-A1 USE OF MULTI-SPECIFIC HUMAN ALBUMIN NANOPARTICLES DECORATED WITH ANTIBODY FRAGMENTS AND LOADED WITH CYTOTOXICS ALB, CD63, ENPEP NSD2 4036/4885G6PD 2334/4885KEAP1 4608/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.