Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2D6 | P10635 | 3/20 | 0.52 |
| ▸ | LMNA | P02545 | 2/20 | 0.52 |
| ▸ | BLM | P54132 | 2/20 | 0.52 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.52 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.52 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.52 |
| ▸ | TSHR | P16473 | 1/20 | 0.52 |
| ▸ | RAB9A | P51151 | 1/20 | 0.52 |
| ▸ | MEN1 | O00255 | 1/20 | 0.52 |
| ▸ | THRB | P10828 | 1/20 | 0.52 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.52 |
| ▸ | CTSC | P53634 | 3/20 | 0.36 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.33 |
| ▸ | CHRM4 | P08173 | 2/20 | 0.33 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.33 |
| ▸ | SLC1A2 | P43004 | 2/20 | 0.33 |
| ▸ | SLC1A1 | P43005 | 2/20 | 0.33 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.33 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1996806 | 1.00 | CYP2D6 (0.52) | CYP2D6LMNABLMALOX15CYP1A2 | |
| SCHEMBL7978226 | 1.00 | CYP2D6 (0.52) | CYP2D6LMNABLMALOX15CYP1A2 | |
| SCHEMBL9359626 | 1.00 | CYP2D6 (0.52) | CYP2D6LMNABLMALOX15CYP1A2 | |
| SCHEMBL1814002 | 1.00 | CYP2D6 (0.52) | CYP2D6LMNABLMALOX15CYP1A2 | |
| SCHEMBL10795076 | 1.00 | CYP2D6 (0.52) | CYP2D6LMNABLMALOX15CYP1A2 | |
| SCHEMBL497178 | 1.00 | CYP2D6 (0.52) | CYP2D6LMNABLMALOX15CYP1A2 | |
| SCHEMBL24866537 | 1.00 | CYP2D6 (0.52) | CYP2D6LMNABLMALOX15CYP1A2 | |
| SCHEMBL9587111 | 1.00 | CYP2D6 (0.52) | CYP2D6LMNABLMALOX15CYP1A2 | |
| SCHEMBL21148 | 1.00 | CYP2D6 (0.52) | CYP2D6LMNABLMALOX15CYP1A2 | |
| SCHEMBL10348708 | 1.00 | CYP2D6 (0.52) | CYP2D6LMNABLMALOX15CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 358 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117865876-A | Method for preparing ramipril intermediate | 浙江华海药业股份有限公司 | 2024-04-12 | — | — | CN | claimed |
| WO-2022117893-A2 | COMBINATION THERAPY FOR PATIENTS HAVING ACUTE AND/OR PERSISTENT DYSPNEA | S-FORM PHARMA (BE) | 2022-06-09 | — | — | WO | claimed |
| EP-2598479-B1 | A METHOD FOR PREPARING RAMIPRIL | AARTI HEALTHCARE LTD (IN) | 2015-04-01 | — | — | EP | claimed |
| EP-2044010-B1 | NEW PHARMACEUTICAL INTERMEDIATES IN THE SYNTHESIS OF ACE-INIHIBITORS AND THE USE THEREOF | EGIS GYOGYSZERGYAR NYILVANOSAN MUEKOEDO RESZVENYTARSASAG (HU) | 2014-01-08 | — | — | EP | claimed |
| EP-2598479-A2 | A METHOD FOR PREPARING RAMIPRIL | Aarti Healthcare Limited (IN) | 2013-06-05 | — | — | EP | claimed |
| US-20130137670-A1 | ZWITTERION SOLUTION FOR LOW-VOLUME THERAPEUTIC DELIVERY | WAYNE STATE UNIVERSITY BOARD OF GOVERNORS (US) | 2013-05-30 | — | — | US | claimed |
| WO-2012063252-A2 | A METHOD FOR PREPARING RAMIPRIL | AARTI HEALTHCARE LIMITED (IN) | 2012-05-18 | — | — | WO | claimed |
| US-20100324304-A1 | IMPROVED RAMIPRIL SYNTHESIS | DSM IP ASSETS B.V. (NL) | 2010-12-23 | — | — | US | claimed |
| US-20100286404-A1 | PHARMACEUTICAL INTERMEDIATES IN THE SYNTHESIS OF ACE-INHIBITORS AND THE USE THEREOF | EGIS GYOGYSZERGYAR NYILVANOSAN MUKODO RESZVENYTARSASAG (HU) | 2010-11-11 | — | — | US | claimed |
| US-20100210604-A1 | ZWITTERION SOLUTION FOR LOW-VOLUME THERAPEUTIC DELIVERY | WAYNE STATE UNIVERSITY BOARD OF GOVERNORS | 2010-08-19 | — | — | US | claimed |
| US-20060159742-A1 | Stabilized individually coated ramipril particles, compositions and methods | KING PHARMACEUTICAL RESEARCH & DEVELOPMENT, INC. | 2006-07-20 | — | — | US | claimed |
| EP-1635792-A1 | STABLE PHARMACEUTICAL COMPOSITIONS OF 2-AZA-BICYCLO[3.3.0]-OCTANE-3-CARBOXYLIC ACID DERIVATIVES | Teva Pharmaceutical Industries Limited (IL) | 2006-03-22 | — | — | EP | claimed |
| US-20050069586-A1 | Stable pharmaceutical compositions of 2-aza-bicyclo [3.3.0]-octane-3-carboxylic acid derivatives | TEVA PHARMACEUTICALS USA, LTD. | 2005-03-31 | — | — | US | claimed |
| WO-2005002548-A1 | STABLE PHARMACEUTICAL COMPOSITIONS OF 2-AZA-BICYCLO[3.3.0]-OCTANE-3-CARBOXYLIC ACID DERIVATIVES | TEVA PHARMACEUTICAL INDUSTRIES LTD. (IL) | 2005-01-13 | — | — | WO | claimed |
| US-6541635-B1 | Silylprotected L-proline derivative or salt is deprotected in presence of a nonaqueous medium containing an organic solvent at a temperature of 5 degree C. to 40 degree C. | EVERLIGHT USA, INC. | 2003-04-01 | — | — | US | claimed |
| EP-0564972-A2 | Peptides with N-terminal modifications having bradykinin antagonistic activity | HOECHST AKTIENGESELLSCHAFT (DE) | 1993-10-13 | — | — | EP | claimed |
| EP-0455133-A2 | Peptide antagonists of bradykinin | HOECHST AKTIENGESELLSCHAFT (DE) | 1991-11-06 | — | — | EP | claimed |
| EP-0117447-B1 | CYCLIC PEPTIDES WITH SOMATOSTATIN ACTIVITY | HOECHST AKTIENGESELLSCHAFT (DE) | 1987-12-09 | — | — | EP | claimed |
| US-4691022-A | Process for the preparation of monocyclic, bicyclic and tricyclic aminoacids | HOECHST AKTIENGESELLSCHAFT (DE) | 1987-09-01 | — | — | US | claimed |
| US-4587258-A | HYPOTENSIVE AGENTS, CONGESTIVE HEART FAILURE | SCHERING CORPORATION (US) | 1986-05-06 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060159742-A1 | Stabilized individually coated ramipril particles, compositions and methods | REN, VASP, PDE12 | CYP2D6 47/4885LMNA 780/4885BLM 4449/4885 |
| US-20130137670-A1 | ZWITTERION SOLUTION FOR LOW-VOLUME THERAPEUTIC DELIVERY | SLC6A11, CA2, CACNA1F | CYP2D6 3452/4885LMNA 3678/4885BLM 3130/4885 |
| US-20100286404-A1 | PHARMACEUTICAL INTERMEDIATES IN THE SYNTHESIS OF ACE-INHIBITORS AND THE USE THEREOF | ACE, AGTR1, REN | CYP2D6 7/4885LMNA 2592/4885BLM 2153/4885 |
| US-20100210604-A1 | ZWITTERION SOLUTION FOR LOW-VOLUME THERAPEUTIC DELIVERY | SLC6A11, CA2, CACNA1F | CYP2D6 3452/4885LMNA 3678/4885BLM 3130/4885 |
| US-20100324304-A1 | IMPROVED RAMIPRIL SYNTHESIS | AVPR2, CYP2D6, AVPR1B | CYP2D6 2/4885LMNA 1744/4885BLM 4828/4885 |
| US-20050069586-A1 | Stable pharmaceutical compositions of 2-aza-bicyclo [3.3.0]-octane-3-carboxylic acid derivatives | AZI2, TPMT, CYP3A43 | CYP2D6 23/4885LMNA 4517/4885BLM 1253/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.