Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | BACE1 | P56817 | 1/20 | 0.37 |
| ▸ | HTR1A | P08908 | 1/20 | 0.36 |
| ▸ | HTR2C | P28335 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4364578 | 1.00 | KDM4E (0.42) | KDM4EKMT2AALDH1A1MEN1ATM | |
| SCHEMBL4362890 | 0.85 | ALDH1A1 (0.45) | KDM4EKMT2AALDH1A1MEN1ATM | |
| SCHEMBL12342861 | 0.82 | ALDH1A1 (0.38) | KDM4EKMT2AALDH1A1MEN1ATM | |
| SCHEMBL9217160 | 0.79 | LMNA (0.48) | KMT2AALDH1A1MEN1TSHR | |
| SCHEMBL12342818 | 0.78 | ALDH1A1 (0.49) | KDM4EKMT2AALDH1A1MEN1ATM | |
| SCHEMBL18911326 | 0.77 | MEN1 (0.46) | KDM4EKMT2AALDH1A1MEN1TSHR | |
| SCHEMBL12342819 | 0.77 | MEN1 (0.44) | KDM4EKMT2AALDH1A1MEN1MAPT | |
| SCHEMBL4359497 | 0.76 | MEN1 (0.41) | KMT2AALDH1A1MEN1MAPTBACE1 | |
| SCHEMBL4359522 | 0.74 | BACE1 (0.39) | KMT2AALDH1A1MEN1MAPTBACE1 | |
| SCHEMBL12342862 | 0.74 | MEN1 (0.38) | KMT2AALDH1A1MEN1MAPTBACE1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8268810-B2 | Lipophilic chelates and their use in imaging | GUERBET (FR) | 2012-09-18 | — | — | US | disclosed |
| US-20090214441-A1 | Lipophilic Chelates and Their Use in Imaging | GUERBET (FR) | 2009-08-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090214441-A1 | Lipophilic Chelates and Their Use in Imaging | SLC40A1, TSPO, SLC47A2 | KDM4E 1946/4885KMT2A 1704/4885ALDH1A1 2637/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.