Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATM | Q13315 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | HTR6 | P50406 | 1/20 | 0.33 |
| ▸ | HTR2A | P28223 | 1/20 | 0.32 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL29674976 | 1.00 | ATM (0.35) | ATMMEN1KMT2AHTR6HTR2A | |
| Hydrochloric Acid SCHEMBL7945423 | 1.00 | ATM (0.35) | ATMMEN1KMT2AHTR6HTR2A | |
| Hydrochloric Acid SCHEMBL30254817 | 0.89 | ATM (0.31) | ATMMEN1KMT2A | |
| Hydrochloric Acid SCHEMBL30255010 | 0.89 | ATM (0.31) | ATMMEN1KMT2A | |
| Hydrochloric Acid SCHEMBL566021 | 0.88 | ATM (0.31) | ATM | |
| Hydrochloric Acid SCHEMBL437960 | 0.83 | MEN1 (0.35) | ATMMEN1KMT2AHTR6HTR2A | |
| Hydrochloric Acid SCHEMBL7947296 | 0.83 | MEN1 (0.35) | ATMMEN1KMT2AHTR6HTR2A | |
| Hydrochloric Acid SCHEMBL439350 | 0.83 | LMNA (0.34) | LMNA | |
| Hydrochloric Acid SCHEMBL2861109 | 0.81 | LMNA (0.33) | MEN1KMT2ASMN1; SMN2LMNA | |
| Hydrochloric Acid SCHEMBL273051 | 0.80 | HTR2A (0.33) | MEN1KMT2AHTR6HTR2ASIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 70 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8969482-B2 | Dynamic modulation of metallocene catalysts | EXXONMOBIL CHEMICAL PATENTS INC. (US) | 2015-03-03 | — | — | US | claimed |
| EP-2760895-A2 | DYNAMIC MODULATION OF METALLOCENE CATALYSTS | Exxon-Mobil Chemical Patents Inc. (US) | 2014-08-06 | — | — | EP | claimed |
| US-20130085232-A1 | Dynamic Modulation of Metallocene Catalysts | EXXONMOBIL CHEMICAL PATENTS INC. (US) | 2013-04-04 | — | — | US | claimed |
| WO-2013048848-A2 | DYNAMIC MODULATION OF METALLOCENE CATALYSTS | EXXONMOBIL CHEMICAL PATENTS INC. (US) | 2013-04-04 | — | — | WO | claimed |
| US-5698645-A | POLYMERIZING AT LEAST ONE CYCLOOLEFIN AND ONE ACYCLIC OLEFIN IN THE PRESENCE OF A METALLOCENE CATALYST AND A COCATALYST | HOECHST AKTIENGESELLSCHAFT (DE) | 1997-12-16 | — | — | US | claimed |
| WO-2024185503-A1 | RESIN MODIFIER AND RESIN COMPOSITION COMPRISING SAME | 東ソー株式会社 | 2024-09-12 | — | — | WO | disclosed |
| US-11192976-B2 | Copolymer, polymer, molding material and resin molded body | ZEON CORPORATION (JP) | 2021-12-07 | — | — | US | disclosed |
| US-20200231745-A1 | COPOLYMER, POLYMER, MOLDING MATERIAL AND RESIN MOLDED BODY | ZEON CORPORATION (JP) | 2020-07-23 | — | — | US | disclosed |
| US-10647811-B2 | Copolymer, polymer, molding material and resin molded body | ZEON CORPORATION (JP) | 2020-05-12 | — | — | US | disclosed |
| US-20180086877-A1 | COPOLYMER, POLYMER, MOLDING MATERIAL AND RESIN MOLDED BODY | ZEON CORPORATION (JP) | 2018-03-29 | — | — | US | disclosed |
| US-9919300-B2 | 1-hexene production process | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2018-03-20 | — | — | US | disclosed |
| CN-107406559-A | Copolymer, polymer, molding material, and resin molded article | 日本瑞翁株式会社 | 2017-11-28 | — | — | CN | disclosed |
| US-5698645-A | POLYMERIZING AT LEAST ONE CYCLOOLEFIN AND ONE ACYCLIC OLEFIN IN THE PRESENCE OF A METALLOCENE CATALYST AND A COCATALYST | HOECHST AKTIENGESELLSCHAFT (DE) | 1997-12-16 | — | — | US | disclosed |
| EP-0612769-B1 | Process for producing ethylene alpha-olefin copolymer | TOSOH CORP (JP) | 1997-11-12 | — | — | EP | disclosed |
| US-5670681-A | Process for preparing a carbon-bridged biscyclopentadiene compound | HOECHST AKTIENGESELLSCHAFT (DE) | 1997-09-23 | — | — | US | disclosed |
| EP-0648786-B1 | Process for producing alpha-olefin polymer | TOSOH CORP (JP) | 1997-07-16 | — | — | EP | disclosed |
| US-5576259-A | POLYMERIZATION CATALYST INCLUDING METALLOCENE COMPOUND, IONIC COMPOUND, ORGANOALUMINUM COMPOUND, AND LEWIS BASE | TOSOH CORPORATION (JP) | 1996-11-19 | — | — | US | disclosed |
| EP-0653445-A1 | Ethylene/alpha-olefin copolymer | Tosoh Corporation (JP) | 1995-05-17 | — | — | EP | disclosed |
| EP-0648786-A1 | Process for producing alpha-olefin polymer | Tosoh Corporation (JP) | 1995-04-19 | — | — | EP | disclosed |
| EP-0612769-A1 | Process for producing ethylene alpha-olefin copolymer | TOSOH CORPORATION (JP) | 1994-08-31 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10647811-B2 | Copolymer, polymer, molding material and resin molded body | MALT1, ALOX15, ALOX5 | ATM 3244/4885MEN1 1724/4885KMT2A 4418/4885 |
| US-20180086877-A1 | COPOLYMER, POLYMER, MOLDING MATERIAL AND RESIN MOLDED BODY | MALT1, ALOX15, ALOX5 | ATM 3244/4885MEN1 1724/4885KMT2A 4418/4885 |
| US-11192976-B2 | Copolymer, polymer, molding material and resin molded body | MALT1, CCT7, ALOX15 | ATM 3772/4885MEN1 2084/4885KMT2A 4338/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.