SCHEMBL4365047

SCHEMBL4365047

O=C(O)c1cc(F)c(O)c(F)c1

nearest known ligand 0.64

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA12 O43570 3/20 0.64
CA1 P00915 3/20 0.64
CA2 P00918 3/20 0.64
CA7 P43166 3/20 0.64
CA9 Q16790 3/20 0.64
CA14 Q9ULX7 3/20 0.64
LMNA P02545 3/20 0.64
ALDH1A1 P00352 2/20 0.64
CA3 P07451 2/20 0.64
CA4 P22748 2/20 0.64
CA6 P23280 2/20 0.64
CA5A P35218 2/20 0.64
CA5B Q9Y2D0 2/20 0.64
KDM4E B2RXH2 2/20 0.64
MAPK1 P28482 2/20 0.64
HSD17B10 Q99714 2/20 0.64
TP53 P04637 1/20 0.64
MAPT P10636 1/20 0.64
SELL P14151 1/20 0.64
HPGD P15428 1/20 0.64

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9787632 0.90 CA12 (0.73) CA12CA1CA2CA7CA9
SCHEMBL10316072 0.84 CA12 (0.52) CA12CA1CA2CA7CA9
SCHEMBL30657986 0.84 CA12 (0.52) CA12CA1CA2CA7CA9
SCHEMBL26653829 0.84 CA12 (0.52) CA12CA1CA2CA7CA9
SCHEMBL6092664 0.84 CA12 (0.52) CA12CA1CA2CA7CA9
SCHEMBL2684340 0.84 TTR (0.72) CA12CA1CA2CA7CA9
SCHEMBL1313079 0.84 TPMT (0.56) CA12CA1CA2CA7CA9
SCHEMBL29998931 0.84 TTR (0.72) CA12CA1CA2CA7CA9
SCHEMBL21837082 0.84 TTR (0.72) CA12CA1CA2CA7CA9
SCHEMBL221480 0.81 CES2 (0.67) CA12CA1CA2CA7CA9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 43 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-111849507-A Fluorine-containing liquid crystal molecule with cholesterol as chiral center and preparation method thereof 智谱纳米科技(上海)有限公司 2020-10-30 CN claimed
US-12497428-B2 Galactoside inhibitor of galectins GALECTO BIOTECH AB (DK) 2025-12-16 US disclosed
WO-2025224512-A1 NOVEL COMPOUND AS 17-BETA-HYDROXYSTEROID DEHYDROGENASE 13 (HSD17B13) INHIBITOR AND PHARMACEUTICAL COMPOSITION COMPRISING SAME 삼진제약주식회사 2025-10-30 WO disclosed
EP-4634169-A1 3-FLUORO-4-HYDROXYBENZMIDE-CONTAINING INHIBITORS AND/OR DEGRADERS AND USES THEREOF Pfizer Inc. (US) 2025-10-22 EP disclosed
EP-4598908-A1 HSD17B13 INHIBITORS AND/OR DEGRADERS Pfizer Inc. (US) 2025-08-13 EP disclosed
US-20240238425-A1 HSD17B13 Inhibitors and/or Degraders PFIZER INC. (US) 2024-07-18 US disclosed
US-20240238425-A1 HSD17B13 Inhibitors and/or Degraders PFIZER INC. (US) 2024-07-18 US disclosed
US-20240238425-A1 HSD17B13 Inhibitors and/or Degraders PFIZER INC. (US) 2024-07-18 US disclosed
WO-2024127297-A1 3-FLUORO-4-HYDROXYBENZMIDE-CONTAINING INHIBITORS AND/OR DEGRADERS AND USES THEREOF PFIZER INC. (US) 2024-06-20 WO disclosed
US-20240150334-A1 HSD17B13 INHIBITORS AND/OR DEGRADERS PFIZER INC. (US) 2024-05-09 US disclosed
US-20060004112-A1 Molecular chains of the liquid crystalline polymer (e.g. polybenzoxazole, polybenzothiazole, and polybenzimidazole) having an ionic disosciative group and molecular chain orientated in a specific direction; allows permeation of hydrogen ions generated at a fuel electrode (anode) to cathode POLYMATECH CO., LTD. 2006-01-05 US disclosed
WO-2005080317-A2 THERAPEUTIC AMIDE DERIVATIVES PFIZER JAPAN, INC. (JP) 2005-09-01 WO disclosed
WO-2005063385-A1 METHOD FOR OXIDIZING SATURATED HYDROCARBONS DSM FINE CHEMICALS AUSTRIA NFG GMBH & CO KG (AT) 2005-07-14 WO disclosed
US-20030216577-A1 Preparation of aromatic and heteroaromatic carboxylic acids by catalytic ozonolysis DSM FINE CHEMICALS AUSTRIA NFG GMBH & COKG (AT) 2003-11-20 US disclosed
EP-1362840-A1 Process for the preparation of aromatic and heteroaromatic carboxylic acids via catalytic ozonolysis DSM Fine Chemicals Austria Nfg GmbH & Co KG (AT) 2003-11-19 EP disclosed
EP-0757028-B1 Process for the preparation of aromatic carbonic acid esters CLARIANT GMBH (DE) 1999-12-29 EP disclosed
US-5874608-A Process for the preparation of esters of aromatic carboxylic acid HOECHST AKTIENGESELLSCHAFT (DE) 1999-02-23 US disclosed
US-5744628-A Process for the preparation of esters of aromatic carboxylic acids HOECHST AKTIENGESELLSCHAFT (DE) 1998-04-28 US disclosed
EP-0811601-A1 Process for the preparation of aromatic carbonic acid esters Clariant GmbH (DE) 1997-12-10 EP disclosed
EP-0757028-A1 Process for the preparation of aromatic carbonic acid esters HOECHST AKTIENGESELLSCHAFT (DE) 1997-02-05 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240238425-A1 HSD17B13 Inhibitors and/or Degraders HSD17B13, HSD17B3, HSD17B1 CA12 2425/4885CA1 3878/4885CA2 3939/4885
US-20240150334-A1 HSD17B13 INHIBITORS AND/OR DEGRADERS HSD17B1, HSD17B3, HSD17B13 CA12 3053/4885CA1 3741/4885CA2 4080/4885
US-12497428-B2 Galactoside inhibitor of galectins LGALS1, LGALS3, LGALS2 CA12 414/4885CA1 1398/4885CA2 1633/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.