SCHEMBL4366582

SCHEMBL4366582

Fc1ccc(-c2cccc3cccnc23)cc1

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
FABP1 P07148 1/20 0.56
KDM4E B2RXH2 2/20 0.54
LMNA P02545 2/20 0.54
MAPT P10636 2/20 0.54
HTT P42858 2/20 0.54
MMP2 P08253 2/20 0.54
TSHR P16473 2/20 0.54
GMNN O75496 1/20 0.54
TP53 P04637 1/20 0.54
HSP90AA1 P07900 1/20 0.54
CYP3A4 P08684 1/20 0.54
CYP2D6 P10635 1/20 0.54
MMP9 P14780 1/20 0.54
ALOX15 P16050 1/20 0.54
NFKB1 P19838 1/20 0.54
MMP8 P22894 1/20 0.54
CCR1 P32246 1/20 0.54
THPO P40225 1/20 0.54
MTOR P42345 1/20 0.54
MMP13 P45452 1/20 0.54

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23733863 0.92 FABP1 (0.50) FABP1KDM4ELMNAMAPTHTT
SCHEMBL26547999 0.91 TOP1 (0.51) FABP1KDM4ELMNAMAPTHTT
SCHEMBL26548418 0.91 TOP1 (0.51) FABP1KDM4ELMNAMAPTHTT
SCHEMBL26548919 0.89 TOP1 (0.50) FABP1KDM4ELMNAMAPTHTT
SCHEMBL26548601 0.89 TOP1 (0.50) FABP1KDM4ELMNAMAPTHTT
SCHEMBL4373392 0.84 LMNA (0.52) FABP1KDM4ELMNAMAPTHTT
SCHEMBL12074320 0.83 MMP2 (0.56) FABP1KDM4ELMNAMAPTHTT
SCHEMBL30592746 0.83 MMP2 (0.56) FABP1KDM4ELMNAMAPTHTT
SCHEMBL4148271 0.82 MMP2 (0.60) KDM4ELMNAMAPTHTTMMP2
SCHEMBL28254626 0.82 BRD4 (0.52) KDM4ELMNAMAPTHTTMMP2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1820227-B1 METAL COMPLEXES AND THEIR USE AS THE EMITTING CONSTITUENT IN ELECTRONIC COMPONENTS, IN PARTICULAR IN ELECTROLUMINESCENT DISPLAY DEVICES MERCK PATENT GMBH (DE) 2014-05-07 EP disclosed
US-8304542-B2 Metal complexes and their use as the emitting constituent in electronic components, in particular in electroluminescent display devices MERCK PATENT GMBH (DE) 2012-11-06 US disclosed
US-8304542-B2 Metal complexes and their use as the emitting constituent in electronic components, in particular in electroluminescent display devices MERCK PATENT GMBH (DE) 2012-11-06 US disclosed
US-8304542-B2 Metal complexes and their use as the emitting constituent in electronic components, in particular in electroluminescent display devices MERCK PATENT GMBH (DE) 2012-11-06 US disclosed
CN-100580972-C Metal complexes MERCK PATENT GMBH 2010-01-13 CN disclosed
US-20090292080-A1 Metal Complexes and Their Use as the Emitting Constituent in Electronic Components, in Particular in Electroluminescent Display Devices MERCK PATENT GMBH (DE) 2009-11-26 US disclosed
US-20090292080-A1 Metal Complexes and Their Use as the Emitting Constituent in Electronic Components, in Particular in Electroluminescent Display Devices MERCK PATENT GMBH (DE) 2009-11-26 US disclosed
US-20090292080-A1 Metal Complexes and Their Use as the Emitting Constituent in Electronic Components, in Particular in Electroluminescent Display Devices MERCK PATENT GMBH (DE) 2009-11-26 US disclosed
CN-101073163-A Metal complexes MERCK PATENT GMBH (DE) 2007-11-14 CN disclosed
EP-1820227-A1 METAL COMPLEXES AND THEIR USE AS THE EMITTING CONSTITUENT IN ELECTRONIC COMPONENTS, IN PARTICULAR IN ELECTROLUMINESCENT DISPLAY DEVICES MERCK PATENT GmbH (DE) 2007-08-22 EP disclosed
WO-2006061182-A1 METAL COMPLEXES AND THEIR USE AS THE EMITTING CONSTITUENT IN ELECTRONIC COMPONENTS, IN PARTICULAR IN ELECTROLUMINESCENT DISPLAY DEVICES MERCK PATENT GMBH (DE) 2006-06-15 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090292080-A1 Metal Complexes and Their Use as the Emitting Constituent in Electronic Components, in Particular in Electroluminescent Display Devices L1CAM, AP1M1, SOD1 FABP1 2004/4885KDM4E 3515/4885LMNA 4037/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.