SCHEMBL436693

SCHEMBL436693

CC1(CCc2ccccc2)CC[Si](C)(C)[Si](C)(C)O1

nearest known ligand 0.38

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
OPRM1 P35372 5/20 0.38
OPRL1 P41146 4/20 0.38
KDM1A O60341 2/20 0.36
MAOA P21397 2/20 0.36
MAOB P27338 2/20 0.36
OPRD1 P41143 2/20 0.35
OPRK1 P41145 2/20 0.35
GAA P10253 1/20 0.34
L3MBTL1 Q9Y468 1/20 0.34
TAAR1 Q96RJ0 2/20 0.33
CYP2A6 P11509 1/20 0.32
HTR2A P28223 1/20 0.32
SMN1; SMN2 Q16637 1/20 0.32
LOXL2 Q9Y4K0 1/20 0.32
BACE1 P56817 2/20 0.32
CYP2D6 P10635 1/20 0.32
SLC6A2 P23975 1/20 0.32
SLC6A4 P31645 1/20 0.32
SLC6A3 Q01959 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27936142 0.79 KDM1A (0.36) OPRM1OPRL1KDM1AMAOAMAOB
SCHEMBL29179725 0.74 OPRM1 (0.35) OPRM1OPRL1KDM1AMAOAMAOB
SCHEMBL8328439 0.73 MAOA (0.39) OPRM1OPRL1KDM1AMAOAMAOB
SCHEMBL7997821 0.71 GAA (0.41) OPRM1OPRL1KDM1AMAOAMAOB
SCHEMBL22013858 0.71 GAA (0.41) OPRM1OPRL1KDM1AMAOAMAOB
SCHEMBL1552116 0.68 OPRM1 (0.36) OPRM1OPRL1MAOAMAOBOPRK1
SCHEMBL7140516 0.67 MAOA (0.35) OPRM1OPRL1KDM1AMAOAMAOB
SCHEMBL22015030 0.66 GAA (0.48) GAAL3MBTL1BACE1
SCHEMBL28233446 0.66 KDM1A (0.37) OPRM1OPRL1KDM1AMAOAMAOB
SCHEMBL15355130 0.64 OPRM1 (0.44) OPRM1OPRL1KDM1AMAOAMAOB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 133 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6300027-B1 Low surface energy photoreceptors XEROX CORPORATION 2001-10-09 US claimed
EP-0531328-A4 LIQUID ANTIPERSPIRANT COMPOSITIONS 1993-04-21 EP claimed
EP-0531337-A4 LIQUID ANTIPERSPIRANT COMPOSITIONS 1993-04-14 EP claimed
EP-0531328-A1 LIQUID ANTIPERSPIRANT COMPOSITIONS THE PROCTER & GAMBLE COMPANY (US) 1993-03-17 EP claimed
EP-0531337-A1 LIQUID ANTIPERSPIRANT COMPOSITIONS THE PROCTER & GAMBLE COMPANY (US) 1993-03-17 EP claimed
US-5095086-A Polysesquisiloxanes GENERAL ELECTRIC COMPANY (US) 1992-03-10 US claimed
EP-0470442-A2 Improved scuff-masking coatings for glass articles GENERAL ELECTRIC COMPANY (US) 1992-02-12 EP claimed
WO-1991018586-A1 LIQUID ANTIPERSPIRANT COMPOSITIONS THE PROCTER & GAMBLE COMPANY (US) 1991-12-12 WO claimed
WO-1991018587-A1 LIQUID ANTIPERSPIRANT COMPOSITIONS THE PROCTER & GAMBLE COMPANY (US) 1991-12-12 WO claimed
EP-2841163-B1 TWO-STEP MASCARA PRODUCT NOXELL CORP (US) 2017-09-20 EP disclosed
CN-104245048-B Two step mascara products 诺赛尔股份有限公司 2017-09-08 CN disclosed
CN-104053702-B The method of preparation sugar silicone copolymers 道康宁公司 2016-06-22 CN disclosed
US-9254247-B2 Mascara system with thickening benefits THE PROCTER & GAMBLE COMPANY (US) 2016-02-09 US disclosed
US-9237992-B2 Two-step mascara product THE PROCTER & GAMBLE COMPANY (US) 2016-01-19 US disclosed
CN-1049785-A The vehicle system that is used for cosmetic composition PROCTER & GAMBLE (US) 1991-03-13 CN disclosed
CN-1049784-A Hair conditioning and Hairstyling composition PROCTER & GAMBLE (US) 1991-03-13 CN disclosed
CN-1049786-A Hair nursing and Hairstyling composition PROCTER & GAMBLE (US) 1991-03-13 CN disclosed
EP-0412710-A2 Vehicle systems for use in cosmetic compositions THE PROCTER & GAMBLE COMPANY (US) 1991-02-13 EP disclosed
EP-0412706-A2 Vehicle systems for use in cosmetic compostions THE PROCTER & GAMBLE COMPANY (US) 1991-02-13 EP disclosed
EP-0412705-A2 Vehicle systems for use in cosmetic compositions THE PROCTER & GAMBLE COMPANY (US) 1991-02-13 EP disclosed