SCHEMBL27936142

SCHEMBL27936142

CC1(CCc2ccccc2)CCC[Si](C)(C)O1

nearest known ligand 0.38

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
KDM1A O60341 2/20 0.36
MAOA P21397 2/20 0.36
MAOB P27338 2/20 0.36
OPRM1 P35372 3/20 0.35
OPRL1 P41146 3/20 0.35
GAA P10253 1/20 0.34
L3MBTL1 Q9Y468 1/20 0.34
BACE1 P56817 2/20 0.32
CYP2D6 P10635 1/20 0.32
SLC6A2 P23975 1/20 0.32
SLC6A4 P31645 1/20 0.32
SLC6A3 Q01959 1/20 0.32
OPRD1 P41143 1/20 0.32
OPRK1 P41145 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29179725 0.94 OPRM1 (0.35) KDM1AMAOAMAOBOPRM1OPRL1
SCHEMBL28519327 0.84 MAOA (0.38) KDM1AMAOAMAOBOPRM1OPRL1
SCHEMBL436693 0.79 OPRM1 (0.38) KDM1AMAOAMAOBOPRM1OPRL1
Styrene SCHEMBL28447161 0.71 ALDH1A1 (0.38)
SCHEMBL7997821 0.71 GAA (0.41) KDM1AMAOAMAOBOPRM1OPRL1
SCHEMBL22013858 0.71 GAA (0.41) KDM1AMAOAMAOBOPRM1OPRL1
SCHEMBL3263252 0.69 HSD11B1 (0.36) OPRM1OPRL1SLC6A2SLC6A4SLC6A3
SCHEMBL28233446 0.69 KDM1A (0.37) KDM1AMAOAMAOBOPRM1OPRL1
SCHEMBL28994499 0.68 SIRT2 (0.32)
SCHEMBL29024225 0.68 SIRT2 (0.32)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-105307631-B Include the cosmetics or dermatological compositions of the UVA- smoke agents for shielding and/or the organic UVA- smoke agents for shielding of hydrophily of merocyanine and the 2- dihydroxy benaophenonel types of amino substitution 莱雅公司 2018-09-18 CN disclosed
CN-104936655-B Include the cosmetics or dermatology emulsion of merocyanine and the emulsification system containing the amphipathic nature polyalcohol comprising at least one 2- acrylamide group methyls propane sulfonic acid unit 莱雅公司 2018-08-17 CN disclosed
CN-105188652-B Cosmetic or dermatological emulsion comprising a merocyanine and an emulsifying system containing an alkali metal salt of a fatty alcohol phosphate 莱雅公司 2018-06-19 CN disclosed
CN-104936575-B Cosmetic or dermatological emulsion comprising a merocyanine and an emulsifying system comprising a gemini surfactant 莱雅公司 2018-01-16 CN disclosed
CN-107375019-A AQUEOUS COSMETIC COMPOSITION COMPRISING ALKYLCELLULOSE 欧莱雅 2017-11-24 CN disclosed
CN-104114144-B The skin care method and/or cosmetic method of protection confrontation UV ray are provided LVMH研究公司 2017-09-01 CN disclosed
CN-104114143-B Cosmetic set for protecting the skin against UV rays LVMH研究公司 2017-08-08 CN disclosed
CN-104363883-B Semi-transparent combination thing comprising silica aerogel particles 莱雅公司 2017-05-31 CN disclosed
CN-105873640-A Transfer device for making up keratin materials 欧莱雅 2016-08-17 CN disclosed
CN-105307631-A Cosmetic or dermatological composition comprising a merocyanine and a uva-screening agent of the amino-substituted 2-hydroxybenzophenone type and/or a hydrophilic organic uva-screening agent OREAL 2016-02-03 CN disclosed
CN-105188652-A Cosmetic or dermatological emulsion comprising a merocyanine and an emulsifying system containing an alkali metal salt of a fatty alcohol phosphate OREAL S A 2015-12-23 CN disclosed
CN-104936575-A Cosmetic or dermatological emulsion comprising a merocyanine and an emulsifying system comprising a gemini surfactant OREAL 2015-09-23 CN disclosed
CN-104936655-A Cosmetic or dermatological emulsion comprising a merocyanine and an emulsifying system containing an amphiphilic polymer comprising at least one 2-acrylamidomethylpropanesulfonic acid unit OREAL 2015-09-23 CN disclosed
CN-104363883-A Translucent composition comprising silica aerogel particles OREAL 2015-02-18 CN disclosed
CN-104114143-A Cosmetic set for protecting the skin against UV rays LVMH RECH 2014-10-22 CN disclosed
CN-104114144-A SKINCARE AND/OR MAKE-UP METHOD PROVIDING PROTECTION AGAINST UV RAYS LVMH RECH 2014-10-22 CN disclosed
CN-103384511-A Aqueous cosmetic compounds comprising alkylcellulose OREAL 2013-11-06 CN disclosed
CN-103269683-A Cosmetic composition and process for curling keratin fibres OREAL 2013-08-28 CN disclosed