Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR4A2 | P43354 | 3/20 | 0.61 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.51 |
| ▸ | NCF1 | P14598 | 1/20 | 0.50 |
| ▸ | CD38 | P28907 | 7/20 | 0.40 |
| ▸ | ELANE | P08246 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.39 |
| ▸ | CASP1 | P29466 | 1/20 | 0.39 |
| ▸ | CASP7 | P55210 | 1/20 | 0.39 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | PSMD14 | O00487 | 1/20 | 0.38 |
| ▸ | MITF | O75030 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | APEX1 | P27695 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11640173 | 0.80 | KDM4E (0.65) | NR4A2KDM4ETDP1NCF1CD38 | |
| SCHEMBL438224 | 0.79 | NR4A2 (0.69) | NR4A2KDM4ETDP1NCF1ELANE | |
| SCHEMBL6588609 | 0.76 | KDM4E (0.48) | KDM4ECD38ALDH1A1HSD17B10CYP3A4 | |
| SCHEMBL439824 | 0.76 | NR4A2 (0.65) | NR4A2KDM4ETDP1NCF1CD38 | |
| SCHEMBL5243405 | 0.76 | NR4A2 (0.65) | NR4A2KDM4ETDP1NCF1ALDH1A1 | |
| SCHEMBL438980 | 0.76 | NR4A2 (1.00) | NR4A2KDM4ETDP1NCF1CD38 | |
| SCHEMBL439735 | 0.76 | NR4A2 (0.65) | NR4A2KDM4ETDP1NCF1CD38 | |
| SCHEMBL20680339 | 0.74 | CD38 (0.59) | NR4A2CD38CYP3A4 | |
| SCHEMBL437287 | 0.73 | NR4A2 (0.61) | NR4A2KDM4ETDP1NCF1ALDH1A1 | |
| SCHEMBL11545600 | 0.72 | TP53 (0.51) | KDM4ETDP1CD38ELANEALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120065166-A1 | Bone Modulators And Methods Therewith | ESPINA VIRGINIA (US) | 2012-03-15 | — | — | US | disclosed |