SCHEMBL4367253

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL8435843	0.90	CYP2C9 (0.46)	NOS1NOS2NOS3CYP2C9NPC1
	SCHEMBL4367226	0.90	NOS3 (0.38)	NOS1NOS2NOS3CYP2C9NPC1
	SCHEMBL10207820	0.88	NOS3 (0.36)	NOS1NOS2NOS3CYP2C9NPC1
	SCHEMBL929600	0.88	NOS2 (0.41)	NOS1NOS2NOS3CYP2C9NPC1
	SCHEMBL10207819	0.88	CYP2C9 (0.37)	NOS1NOS2NOS3CYP2C9NPC1
	SCHEMBL712264	0.88	NOS3 (0.37)	NOS1NOS2NOS3CYP2C9NPC1
	SCHEMBL712266	0.88	NOS3 (0.37)	NOS1NOS2NOS3CYP2C9NPC1
	SCHEMBL714129	0.88	NOS3 (0.35)	NOS1NOS2NOS3CYP2C9LTA4H
	SCHEMBL714130	0.88	NOS3 (0.35)	NOS1NOS2NOS3CYP2C9LTA4H
	SCHEMBL713533	0.87	NOS3 (0.36)	NOS1NOS2NOS3CYP2C9NPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.