SCHEMBL4367226

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL930215	0.92	GRM4 (0.39)	NOS3NOS1NOS2TP53SMN1; SMN2
	SCHEMBL4367253	0.90	NOS1 (0.39)	NOS3NOS1NOS2TP53SMN1; SMN2
	SCHEMBL8435843	0.83	CYP2C9 (0.46)	NOS3NOS1NOS2TP53SMN1; SMN2
	SCHEMBL929600	0.82	NOS2 (0.41)	NOS3NOS1NOS2TP53SMN1; SMN2
	SCHEMBL712266	0.82	NOS3 (0.37)	NOS3NOS1NOS2TP53SMN1; SMN2
	SCHEMBL710468	0.81	NOS3 (0.38)	NOS3NOS1NOS2TP53SMN1; SMN2
	SCHEMBL712693	0.81	NOS3 (0.36)	NOS3NOS1NOS2TP53SMN1; SMN2
	SCHEMBL712692	0.81	NOS3 (0.36)	NOS3NOS1NOS2TP53SMN1; SMN2
	SCHEMBL710422	0.81	CYP2C9 (0.40)	TP53SMN1; SMN2ALDH1A1CYP3A4TSHR
	SCHEMBL12908485	0.81	NOS3 (0.37)	NOS3NOS1NOS2TP53SMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.