Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GHSR | Q92847 | 1/20 | 0.42 |
| ▸ | ADRB3 | P13945 | 3/20 | 0.35 |
| ▸ | NR1H4 | Q96RI1 | 8/20 | 0.35 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.34 |
| ▸ | F10 | P00742 | 1/20 | 0.33 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.33 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL346051 | 0.75 | CA1 (0.47) | ADRB3HDAC8ADRB1 | |
| SCHEMBL459845 | 0.75 | FAAH (0.49) | GHSRADRB3HDAC8ADRB1HDAC1 | |
| SCHEMBL10260016 | 0.75 | FAAH (0.51) | GHSRADRB3HDAC8ADRB1HDAC1 | |
| SCHEMBL436179 | 0.74 | GRIA2 (0.35) | GHSRHDAC8HDAC1HDAC2 | |
| SCHEMBL461537 | 0.74 | RXRA (0.47) | GHSRADRB3HDAC8HDAC1HDAC2 | |
| SCHEMBL461316 | 0.73 | MCHR1 (0.45) | GHSRADRB3HDAC8 | |
| SCHEMBL436855 | 0.73 | GHSR (0.46) | GHSRADRB3HDAC8HDAC1TP53 | |
| SCHEMBL10197736 | 0.73 | HDAC1 (0.53) | HDAC8HDAC1HDAC2 | |
| SCHEMBL459943 | 0.72 | GRIA2 (0.53) | GHSRHDAC8LMNATHRB | |
| SCHEMBL10197667 | 0.72 | GRIA2 (0.53) | GHSRHDAC1TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012012320-A1 | SUBSTITUTED HYDROXAMIC ACIDS AND USES THEREOF | MILLENIUM PHARMACEUTICALS, INC. (US) | 2012-01-26 | — | — | WO | disclosed |