Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 3/20 | 0.60 |
| ▸ | ADORA1 | P30542 | 4/20 | 0.48 |
| ▸ | ADORA2A | P29274 | 3/20 | 0.48 |
| ▸ | MAPT | P10636 | 4/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.42 |
| ▸ | MEN1 | O00255 | 3/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | HPGD | P15428 | 3/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.42 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.42 |
| ▸ | CDK2 | P24941 | 1/20 | 0.42 |
| ▸ | CCNA1 | P78396 | 1/20 | 0.42 |
| ▸ | ASIC3 | Q9UHC3 | 1/20 | 0.41 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.40 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.40 |
| ▸ | GLA | P06280 | 1/20 | 0.40 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3631562 | 0.81 | CCR6 (0.44) | ACHEADORA1ADORA2AMAPTKDM4E | |
| SCHEMBL437545 | 0.80 | ADORA1 (0.55) | ACHEADORA1ADORA2AMAPTKDM4E | |
| SCHEMBL439581 | 0.80 | ACHE (0.51) | ACHEADORA1ADORA2AMAPTKDM4E | |
| SCHEMBL23820020 | 0.76 | KDM4E (0.52) | ADORA1ADORA2AMAPTKDM4EMEN1 | |
| SCHEMBL2873300 | 0.75 | ACHE (1.00) | ACHEADORA1ADORA2AMAPTKDM4E | |
| SCHEMBL439824 | 0.75 | NR4A2 (0.65) | ADORA1MAPTKDM4EALDH1A1HPGD | |
| SCHEMBL437510 | 0.74 | RXFP1 (0.52) | ACHEADORA1ADORA2AMAPTKDM4E | |
| SCHEMBL28327623 | 0.74 | KDM4E (0.53) | ACHEADORA1ADORA2AMAPTKDM4E | |
| SCHEMBL28516025 | 0.73 | ACHE (0.93) | ACHEADORA1ADORA2AMAPTKDM4E | |
| SCHEMBL15919363 | 0.72 | ACHE (0.77) | ACHEMAPTKDM4EMEN1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120065166-A1 | Bone Modulators And Methods Therewith | ESPINA VIRGINIA (US) | 2012-03-15 | — | — | US | disclosed |