Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 2/20 | 0.51 |
| ▸ | ADORA2A | P29274 | 3/20 | 0.51 |
| ▸ | ADORA1 | P30542 | 3/20 | 0.51 |
| ▸ | MEN1 | O00255 | 5/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.43 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.40 |
| ▸ | MAPT | P10636 | 3/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.40 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.40 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.40 |
| ▸ | CDK2 | P24941 | 1/20 | 0.40 |
| ▸ | CCNA1 | P78396 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | RECQL | P46063 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 4/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL436729 | 0.80 | ACHE (0.60) | ACHEADORA2AADORA1MEN1KMT2A | |
| SCHEMBL437545 | 0.79 | ADORA1 (0.55) | ACHEADORA2AADORA1MEN1KMT2A | |
| SCHEMBL437510 | 0.79 | RXFP1 (0.52) | ACHEADORA2AADORA1MEN1KMT2A | |
| SCHEMBL442131 | 0.76 | NR4A2 (0.45) | MEN1KMT2AALDH1A1KDM4EMAPT | |
| SCHEMBL440237 | 0.73 | ACHE (0.59) | ACHEADORA2AADORA1MEN1KMT2A | |
| SCHEMBL437498 | 0.72 | NOS2 (0.50) | ALDH1A1KDM4EMAPT | |
| SCHEMBL27469565 | 0.71 | ACHE (0.70) | ACHEADORA2AADORA1MEN1KMT2A | |
| SCHEMBL25362186 | 0.71 | LMNA (0.47) | MEN1KMT2AALDH1A1KDM4EMAPT | |
| SCHEMBL25361927 | 0.70 | ABCG2 (0.41) | MEN1KMT2AAGTR1KDM4EMAPT | |
| SCHEMBL23820020 | 0.70 | KDM4E (0.52) | ADORA2AADORA1MEN1KMT2AAGTR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120065166-A1 | Bone Modulators And Methods Therewith | ESPINA VIRGINIA (US) | 2012-03-15 | — | — | US | disclosed |