Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXFP1 | Q9HBX9 | 3/20 | 0.52 |
| ▸ | TP53 | P04637 | 1/20 | 0.52 |
| ▸ | ACHE | P22303 | 1/20 | 0.51 |
| ▸ | ADORA2A | P29274 | 3/20 | 0.51 |
| ▸ | ADORA1 | P30542 | 3/20 | 0.51 |
| ▸ | NQO2 | P16083 | 1/20 | 0.43 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.41 |
| ▸ | PTGFR | P43088 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 3/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | DHODH | Q02127 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL439581 | 0.79 | ACHE (0.51) | ACHEADORA2AADORA1SLC2A1MEN1 | |
| SCHEMBL437545 | 0.77 | ADORA1 (0.55) | ACHEADORA2AADORA1SLC2A1MEN1 | |
| SCHEMBL442077 | 0.76 | NR4A2 (0.45) | ACHENQO2MEN1KMT2AKDM4E | |
| SCHEMBL437369 | 0.75 | ACHE (0.67) | RXFP1ACHEADORA2AADORA1SLC2A1 | |
| SCHEMBL436729 | 0.74 | ACHE (0.60) | ACHEADORA2AADORA1MEN1KMT2A | |
| SCHEMBL440237 | 0.73 | ACHE (0.59) | RXFP1ACHEADORA2AADORA1SLC2A1 | |
| SCHEMBL440057 | 0.72 | NOS2 (0.42) | NQO2KDM4EALDH1A1 | |
| SCHEMBL23622861 | 0.71 | KDM4E (0.63) | ACHEADORA2AADORA1MEN1KMT2A | |
| SCHEMBL438920 | 0.71 | ACHE (0.70) | RXFP1ACHEADORA2AADORA1SLC2A1 | |
| SCHEMBL15646642 | 0.70 | DHODH (0.43) | RXFP1TP53NQO2PTGFRALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120065166-A1 | Bone Modulators And Methods Therewith | ESPINA VIRGINIA (US) | 2012-03-15 | — | — | US | disclosed |