Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.38 |
| ▸ | MEN1 | O00255 | 3/20 | 0.38 |
| ▸ | KCNN4 | O15554 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.37 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | KCNA3 | P22001 | 1/20 | 0.36 |
| ▸ | ACSS2 | Q9NR19 | 1/20 | 0.36 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4367360 | 1.00 | KMT2A (0.38) | KMT2AMEN1KCNN4HTTADRB2 | |
| SCHEMBL4374348 | 0.85 | MAPT (0.48) | KMT2AMEN1ADRB2MAPTALDH1A1 | |
| SCHEMBL4374354 | 0.85 | MAPT (0.48) | KMT2AMEN1ADRB2MAPTALDH1A1 | |
| SCHEMBL6306730 | 0.82 | KIF11 (0.36) | KMT2AMEN1KCNN4HTTMAPT | |
| SCHEMBL14043085 | 0.81 | KCNN4 (0.55) | KCNN4ADRB2ALDH1A1KDM4E | |
| SCHEMBL27243562 | 0.81 | KCNN4 (0.55) | KCNN4ADRB2ALDH1A1KDM4E | |
| SCHEMBL27243564 | 0.81 | KCNN4 (0.55) | KCNN4ADRB2ALDH1A1KDM4E | |
| SCHEMBL4362996 | 0.81 | ALDH1A1 (0.42) | KMT2AMEN1KCNN4HTTALDH1A1 | |
| SCHEMBL2490295 | 0.80 | KCNN4 (0.61) | KMT2AMEN1KCNN4HTTALDH1A1 | |
| SCHEMBL4367357 | 0.79 | KIF11 (0.44) | KMT2AMEN1KCNN4HTTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1908829-B1 | OLIGONUCLEOTIDE PROBE | NAT INST OF ADVANCED IND SCIEN (JP) | 2014-01-08 | — | — | EP | disclosed |
| US-7491857-B2 | Oligonucleotide probe | NATIONAL INSTITUTE OF ADVANCED INDUSTRIAL SCIENCE AND TECHNOLOGY (JP) | 2009-02-17 | — | — | US | disclosed |
| US-20080227968-A1 | Oligonucleotide Probe | NATIONAL INSTITUTE OF ADVANCED INDUSTRIAL SCIENCE AND TECHNOLOGY (JP) | 2008-09-18 | — | — | US | disclosed |
| EP-1908829-A1 | OLIGONUCLEOTIDE PROBE | National Institute of Advanced Industrial Science and Technology (JP) | 2008-04-09 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080227968-A1 | Oligonucleotide Probe | APEX1, RNGTT, RNASEH1 | KMT2A 3173/4885MEN1 1946/4885KCNN4 2232/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.