Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRCP | P42785 | 5/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | HTR2A | P28223 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | PNMT | P11086 | 1/20 | 0.36 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | ATM | Q13315 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29990541 | 0.85 | PRCP (0.67) | PRCPMEN1KMT2ACYP3A4CYP2D6 | |
| SCHEMBL12321732 | 0.85 | PRCP (0.67) | PRCPMEN1KMT2ACYP3A4CYP2D6 | |
| SCHEMBL23873992 | 0.85 | PRCP (0.67) | PRCPMEN1KMT2ACYP3A4CYP2D6 | |
| SCHEMBL6263810 | 0.80 | PRCP (0.51) | PRCPCYP3A4CYP2D6HTR2AALDH1A1 | |
| SCHEMBL28454102 | 0.79 | PRCP (0.50) | PRCPMEN1KMT2ACYP3A4CYP2D6 | |
| SCHEMBL31514911 | 0.76 | PNMT (0.52) | PRCPMEN1KMT2ACYP3A4CYP2D6 | |
| SCHEMBL11771819 | 0.74 | PRCP (0.36) | PRCPMEN1KMT2ACYP3A4CYP2D6 | |
| SCHEMBL27457448 | 0.73 | PRCP (0.45) | PRCPCYP3A4CYP2D6HTR2AALDH1A1 | |
| SCHEMBL28255642 | 0.73 | PRCP (0.36) | PRCPMEN1KMT2ACYP3A4CYP2D6 | |
| SCHEMBL28737128 | 0.71 | FFAR1 (0.37) | PRCPCYP2D6ALDH1A1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090291983-A1 | 3-Oxoisoindoline-1-Carboxamide Derivatives as Analgesic Agents | ASTRAZENECA AB (SE) | 2009-11-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090291983-A1 | 3-Oxoisoindoline-1-Carboxamide Derivatives as Analgesic Agents | OPRD1, OPRK1, OPRM1 | PRCP 2732/4885MEN1 2067/4885KMT2A 1653/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.