Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.49 |
| ▸ | GFER | P55789 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.49 |
| ▸ | GAA | P10253 | 4/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.48 |
| ▸ | HPGD | P15428 | 2/20 | 0.48 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | ATM | Q13315 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 2/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | HCRTR1 | O43613 | 2/20 | 0.47 |
| ▸ | KCNK3 | O14649 | 1/20 | 0.46 |
| ▸ | KCNK9 | Q9NPC2 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4180616 | 0.86 | L3MBTL1 (0.65) | L3MBTL1NPSR1MAPK1ALDH1A1GAA | |
| SCHEMBL29250428 | 0.80 | GAA (0.58) | L3MBTL1NPSR1MAPK1GFERALDH1A1 | |
| SCHEMBL2867681 | 0.80 | GFER (0.59) | MAPK1GFERALDH1A1GAAKDM4E | |
| SCHEMBL15334093 | 0.79 | PTGDR2 (0.53) | L3MBTL1NPSR1HPGDHTTRAB9A | |
| SCHEMBL13687512 | 0.79 | CTNNB1 (0.68) | L3MBTL1MAPK1GFERALDH1A1GAA | |
| SCHEMBL8948862 | 0.78 | IDO1 (0.51) | L3MBTL1MAPK1GFERALDH1A1GAA | |
| SCHEMBL8954770 | 0.78 | GAA (0.51) | L3MBTL1MAPK1GFERALDH1A1GAA | |
| SCHEMBL9850074 | 0.77 | CYP2C19 (0.69) | MAPK1GFERALDH1A1GAAKDM4E | |
| SCHEMBL27511977 | 0.76 | POLB (0.55) | NPSR1MAPK1GFERALDH1A1GAA | |
| SCHEMBL4114974 | 0.75 | CTSD (0.69) | MAPK1ALDH1A1GAAHPGDRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101445437-B | Improved process for the catalytic synthesis of diaryl ethers | SALTIGO GMBH | 2014-07-02 | — | — | CN | disclosed |
| EP-2065357-B1 | Improved process for the catalytic synthesis of diaryl ethers | SALTIGO GMBH (DE) | 2014-04-23 | — | — | EP | disclosed |
| US-8304550-B2 | Process for the catalytic synthesis of diaryl ethers | SALTIGO GMBH (DE) | 2012-11-06 | — | — | US | disclosed |
| US-20090143594-A1 | PROCESS FOR THE CATALYTIC SYNTHESIS OF DIARYL ETHERS | SALTIGO GMBH (DE) | 2009-06-04 | — | — | US | disclosed |
| EP-2065356-A1 | Improved process for the catalytic synthesis of diaryl ethers | Saltigo GmbH (DE) | 2009-06-03 | — | — | EP | disclosed |
| EP-2065357-A1 | Improved process for the catalytic synthesis of diaryl ethers | Saltigo GmbH (DE) | 2009-06-03 | — | — | EP | disclosed |
| CN-101445437-A | Improved process for the catalytic synthesis of diaryl ethers | SALTIGO GMBH (DE) | 2009-06-03 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090143594-A1 | PROCESS FOR THE CATALYTIC SYNTHESIS OF DIARYL ETHERS | ARSA, AHR, AOC2 | L3MBTL1 4811/4885NPSR1 1831/4885MAPK1 1408/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.