SCHEMBL4367783

SCHEMBL4367783

CCc1ccc2cc(C=O)ccc2c1

nearest known ligand 0.55

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP2A6 P11509 7/20 0.55
CYP1A2 P05177 1/20 0.55
ALDH1A1 P00352 5/20 0.51
LMNA P02545 1/20 0.51
MAPT P10636 1/20 0.51
HPGD P15428 1/20 0.51
SMN1; SMN2 Q16637 1/20 0.51
RAB9A P51151 2/20 0.47
AKR1C3 P42330 1/20 0.45
AKR1C2 P52895 1/20 0.45
HCAR2 Q8TDS4 1/20 0.42
ALDH1A3 P47895 3/20 0.40
ALDH3A1 P30838 2/20 0.39
MAOA P21397 1/20 0.39
MAOB P27338 1/20 0.39
AOX1 Q06278 1/20 0.39
TACR2 P21452 1/20 0.39
TSHR P16473 1/20 0.38
NPC1 O15118 1/20 0.38
TDP1 Q9NUW8 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29195519 0.94 CYP2A6 (0.53) CYP2A6CYP1A2ALDH1A1LMNAMAPT
SCHEMBL13475717 0.80 RAB9A (0.47) CYP2A6ALDH1A1RAB9AHCAR2AOX1
SCHEMBL1920295 0.80 CYP1A2 (0.55) CYP2A6CYP1A2ALDH1A1LMNAMAPT
SCHEMBL977774 0.80 CYP2A6 (0.54) CYP2A6ALDH1A1RAB9ATSHRTDP1
SCHEMBL29407167 0.80 CYP2A6 (0.80) CYP2A6CYP1A2ALDH1A1LMNAMAPT
SCHEMBL347592 0.80 CYP2A6 (0.80) CYP2A6CYP1A2ALDH1A1LMNAMAPT
SCHEMBL11739548 0.79 CYP1A2 (0.59) CYP2A6CYP1A2ALDH1A1LMNAMAPT
SCHEMBL181524 0.79 PLA2G4A (0.51) ALDH1A1LMNAHCAR2TACR2
SCHEMBL154747 0.78 ALDH1A1 (0.68) CYP2A6ALDH1A1LMNAMAPTHPGD
SCHEMBL182937 0.77 RAB9A (0.45) CYP2A6CYP1A2ALDH1A1MAPTHPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2024082-A2 PROCESS AND CATALYST FOR OXIDIZING AROMATIC COMPOUNDS BP Corporation North America Inc. (US) 2009-02-18 EP disclosed
WO-2007133973-A2 PROCESS AND CATALYST FOR OXIDIZING AROMATIC COMPOUNDS BP CORPORATION NORTH AMERICA INC. (US) 2007-11-22 WO disclosed