SCHEMBL182937

SCHEMBL182937

C=CCc1ccc2cc(C=O)ccc2c1

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
RAB9A P51151 1/20 0.45
XDH P47989 1/20 0.44
ALDH1A1 P00352 6/20 0.43
MAPT P10636 3/20 0.43
PPARG P37231 2/20 0.43
PPARD Q03181 2/20 0.43
KDM4E B2RXH2 1/20 0.43
MEN1 O00255 1/20 0.43
ALDH2 P05091 1/20 0.43
GAA P10253 1/20 0.43
GABRA1 P14867 1/20 0.43
AKR1B1 P15121 1/20 0.43
HPGD P15428 1/20 0.43
CNR1 P21554 1/20 0.43
CNR2 P34972 1/20 0.43
GABRB2 P47870 1/20 0.43
KMT2A Q03164 1/20 0.43
NPSR1 Q6W5P4 1/20 0.43
ESR1 P03372 1/20 0.42
ESR2 Q92731 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3259762 0.84 XDH (0.58) XDHALDH1A1MAPTPPARGPPARD
SCHEMBL253471 0.80 XDH (0.54) XDHALDH1A1MAPTPPARGPPARD
SCHEMBL198193 0.80 XDH (0.54) XDHALDH1A1MAPTPPARGPPARD
SCHEMBL7043823 0.80 XDH (0.54) XDHALDH1A1MAPTPPARGPPARD
SCHEMBL11494827 0.80 XDH (0.54) XDHALDH1A1MAPTPPARGPPARD
SCHEMBL7055734 0.80 XDH (0.54) XDHALDH1A1MAPTPPARGPPARD
SCHEMBL676468 0.80 ALDH1A1 (0.48) XDHALDH1A1MAPTPPARGPPARD
SCHEMBL11747770 0.79 RAB9A (0.39) RAB9AXDHALDH1A1MAPTPPARG
SCHEMBL7555913 0.78 XDH (0.56) XDHALDH1A1MAPTPPARGPPARD
SCHEMBL4367783 0.77 CYP2A6 (0.55) RAB9AALDH1A1MAPTHPGDHCAR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2679592-B1 NOVEL HETEROCYCLIC COMPOUND, METHOD FOR PRODUCING INTERMEDIATE THEREFOR, AND USE THEREOF NIPPON KAYAKU KK (JP) 2018-10-03 EP disclosed
EP-2889301-B1 Novel heterocyclic compound, method for producing intermediate therefor, and use thereof NIPPON KAYAKU KK (JP) 2017-10-25 EP disclosed
US-9796727-B2 Field effect transistor NIPPON KAYAKU KABUSHIKI KAISHA (JP) 2017-10-24 US disclosed
EP-2402348-B1 FIELD EFFECT TRANSISTOR NIPPON KAYAKU KK (JP) 2017-04-12 EP disclosed
EP-2889301-A1 Novel heterocyclic compound, method for producing intermediate therefor, and use thereof NIPPON KAYAKU KABUSHIKI KAISHA (JP) 2015-07-01 EP disclosed
US-9018630-B2 Heterocyclic dinaphtho thieno thiophene (DNTT) compounds for use as organic semiconductor thin films in field effect transistors and related methods NIPPON KAYAKU KABUSHIKI KAISHA (JP) 2015-04-28 US disclosed
US-20130330876-A1 Novel Heterocyclic Compound, Method For Producing Intermediate Therefor, And Use Thereof NIPPON KAYAKU KABUSHIKI KAISHA (JP) 2013-12-12 US disclosed
EP-2402348-A1 FIELD EFFECT TRANSISTOR Hiroshima University (JP) 2012-01-04 EP disclosed
US-5053164-A For high speed switching MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) 1991-10-01 US disclosed
US-4943651-A Novel substitued naphthalene compounds and liquid crystal compositions containing same MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) 1990-07-24 US disclosed
EP-0332409-A2 Novel substituted naphthalene compounds and liquid crystal compositions containing same MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) 1989-09-13 EP disclosed