SCHEMBL4367944

SCHEMBL4367944

CC(=O)Oc1ccc(C(N)=S)cc1

nearest known ligand 0.59

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ELANE P08246 3/20 0.58
HSD17B10 Q99714 1/20 0.56
LMNA P02545 3/20 0.55
MAPT P10636 3/20 0.50
MEN1 O00255 2/20 0.50
KMT2A Q03164 2/20 0.50
POLB P06746 1/20 0.50
PKM P14618 1/20 0.50
ESR1 P03372 1/20 0.50
PGR P06401 1/20 0.50
CHRM2 P08172 1/20 0.50
ADORA3 P0DMS8 1/20 0.50
AR P10275 1/20 0.50
CHRM1 P11229 1/20 0.50
SLC6A2 P23975 1/20 0.50
SLC6A3 Q01959 1/20 0.50
GAA P10253 2/20 0.46
ALDH1A1 P00352 1/20 0.46
HSP90AA1 P07900 1/20 0.46
SMN1; SMN2 Q16637 2/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10045851 0.83 ELANE (0.62) ELANEHSD17B10LMNAMAPTMEN1
SCHEMBL9391321 0.83 PARP10 (0.63) ELANEHSD17B10LMNAMAPTMEN1
SCHEMBL10500415 0.82 ELANE (0.66) ELANEHSD17B10LMNAMAPTMEN1
SCHEMBL9339013 0.81 ELANE (0.83) ELANEHSD17B10LMNAMAPTMEN1
SCHEMBL27500022 0.80 PRSS1 (0.59) ELANEHSD17B10LMNAMAPTMEN1
SCHEMBL2885742 0.80 PTGS2 (0.60) ELANEHSD17B10LMNAMAPTKMT2A
SCHEMBL269329 0.80 LMNA (0.80) ELANEHSD17B10LMNAMAPTMEN1
SCHEMBL10045877 0.79 SMN1; SMN2 (0.43) LMNAMAPTPKMALDH1A1SMN1; SMN2
SCHEMBL17369681 0.79 ELANE (0.68) ELANE
SCHEMBL5831547 0.79 ELANE (0.67) ELANEHSD17B10LMNAMAPTMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 63 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260103775-A1 PROCESS FOR LEACHING METAL SULFIDES WITH REAGENTS HAVING THIOCARBONYL FUNCTIONAL GROUPS JETTI RESOURCES, LLC (US) 2026-04-16 US claimed
US-12416066-B2 Process for leaching metal sulfides with reagents having thiocarbonyl functional groups JETTI RESOURCES, LLC (US) 2025-09-16 US claimed
EP-4461833-A1 PROCESS FOR LEACHING METAL SULFIDES WITH REAGENTS HAVING THIOCARBONYL FUNCTIONAL GROUPS Jetti Resources, LLC (US) 2024-11-13 EP claimed
US-20240336991-A1 PROCESS FOR LEACHING METAL SULFIDES WITH REAGENTS HAVING THIOCARBONYL FUNCTIONAL GROUPS JETTI RESOURCES, LLC (US) 2024-10-10 US claimed
US-12049681-B2 Process for leaching metal sulfides with reagents having thiocarbonyl functional groups JETTI RESOURCES, LLC (US) 2024-07-30 US claimed
EP-3283661-B1 PROCESS FOR LEACHING METAL SULFIDES WITH REAGENTS HAVING THIOCARBONYL FUNCTIONAL GROUPS JETTI RESOURCES LLC (US) 2024-06-05 EP claimed
US-20240167121-A1 PROCESS FOR LEACHING METAL SULFIDES WITH REAGENTS HAVING THIOCARBONYL FUNCTIONAL GROUPS JETTI RESOURCES, LLC (US) 2024-05-23 US claimed
US-11859263-B2 Process for leaching metal sulfides with reagents having thiocarbonyl functional groups JETTI RESOURCES, LLC (US) 2024-01-02 US claimed
CN-107532229-B Process for leaching metal sulphides with an agent having a thiocarbonyl function 不列颠哥伦比亚大学 2021-10-08 CN claimed
US-10961604-B2 Process for leaching metal sulfides with reagents having thiocarbonyl functional groups THE UNIVERSITY OF BRITISH COLUMBIA (CA) 2021-03-30 US claimed
US-10954583-B2 Process for leaching metal sulfides with reagents having thiocarbonyl functional groups THE UNIVERSITY OF BRITISH COLUMBIA (CA) 2021-03-23 US claimed
US-20200181737-A1 Process for Leaching Metal Sulfides with Reagents Having Thiocarbonyl Functional Groups JETTI RESOURCES, LLC 2020-06-11 US claimed
US-20200149131-A1 Process for Leaching Metal Sulfides with Reagents Having Thiocarbonyl Functional Groups JETTI RESOURCES, LLC 2020-05-14 US claimed
US-20200048736-A1 PROCESS FOR LEACHING METAL SULFIDES WITH REAGENTS HAVING THIOCARBONYL FUNCTIONAL GROUPS JETTI RESOURCES, LLC 2020-02-13 US claimed
US-20260103775-A1 PROCESS FOR LEACHING METAL SULFIDES WITH REAGENTS HAVING THIOCARBONYL FUNCTIONAL GROUPS JETTI RESOURCES, LLC (US) 2026-04-16 US disclosed
US-12416066-B2 Process for leaching metal sulfides with reagents having thiocarbonyl functional groups JETTI RESOURCES, LLC (US) 2025-09-16 US disclosed
EP-4461833-A1 PROCESS FOR LEACHING METAL SULFIDES WITH REAGENTS HAVING THIOCARBONYL FUNCTIONAL GROUPS Jetti Resources, LLC (US) 2024-11-13 EP disclosed
US-7498355-B2 Derivatives of 4- or 5-aminosalicylic acid ANTIBE THERAPEUTICS INC. (CA) 2009-03-03 US disclosed
WO-2008009118-A1 4-HYDROXYTHIOBENZAMIDE DERIVATIVES OF DRUGS ANTIBE THERAPEUTICS INC. (CA) 2008-01-24 WO disclosed
US-4356185-A ANTIINFLAMMATORY AGENTS JOHN WYETH & BROTHER LIMITED (GB) 1982-10-26 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260103775-A1 PROCESS FOR LEACHING METAL SULFIDES WITH REAGENTS HAVING THIOCARBONYL FUNCTIONAL GROUPS TST, FECH, SLC6A12 ELANE 2972/4885HSD17B10 1036/4885LMNA 4643/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.