Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR1 | P21554 | 1/20 | 0.39 |
| ▸ | FAAH | O00519 | 6/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | CNR2 | P34972 | 2/20 | 0.34 |
| ▸ | ACKR3 | P25106 | 1/20 | 0.34 |
| ▸ | CRHR1 | P34998 | 2/20 | 0.34 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4369770 | 0.92 | CNR1 (0.48) | CNR1FAAHCRHR1 | |
| SCHEMBL4367963 | 0.91 | CNR1 (0.47) | CNR1KDM4EALDH1A1HPGDTSHR | |
| SCHEMBL4373504 | 0.88 | CNR1 (0.50) | CNR1ALDH1A1HPGDCNR2ACKR3 | |
| SCHEMBL4368598 | 0.88 | CNR2 (0.42) | CNR1TSHRCNR2 | |
| SCHEMBL4542690 | 0.84 | EPHX1 (0.39) | FAAHKDM4EALDH1A1HPGDTSHR | |
| SCHEMBL4423581 | 0.83 | CNR1 (0.46) | CNR1FAAH | |
| SCHEMBL4371549 | 0.83 | CNR1 (0.57) | CNR1CNR2CRHR1 | |
| SCHEMBL4375089 | 0.81 | CNR1 (0.39) | CNR1FAAHACKR3CHRM3 | |
| SCHEMBL4374742 | 0.80 | TSHR (0.42) | CNR1FAAHKDM4EALDH1A1HPGD | |
| SCHEMBL4376155 | 0.80 | CNR1 (0.39) | CNR1KDM4EALDH1A1HPGDTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1749002-B1 | PYRROLE OR IMIDAZOLE AMIDES FOR TREATING OBESITY | HOFFMANN LA ROCHE (CH) | 2009-05-27 | — | — | EP | claimed |