Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR1 | P21554 | 1/20 | 0.48 |
| ▸ | CRHR1 | P34998 | 14/20 | 0.39 |
| ▸ | CRHR2 | Q13324 | 3/20 | 0.37 |
| ▸ | FAAH | O00519 | 1/20 | 0.36 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4372987 | 0.92 | CNR1 (0.39) | CNR1CRHR1FAAH | |
| SCHEMBL4371549 | 0.91 | CNR1 (0.57) | CNR1CRHR1CRHR2 | |
| SCHEMBL4371262 | 0.88 | CNR1 (0.61) | CNR1CRHR1CRHR2 | |
| SCHEMBL4368758 | 0.88 | CNR1 (0.51) | CNR1CRHR1FAAHMRGPRX4 | |
| SCHEMBL4375499 | 0.86 | CNR1 (0.49) | CNR1CRHR1FAAHMRGPRX4 | |
| SCHEMBL4542690 | 0.83 | EPHX1 (0.39) | FAAH | |
| SCHEMBL4367963 | 0.83 | CNR1 (0.47) | CNR1CRHR1 | |
| SCHEMBL4369412 | 0.80 | CNR1 (0.49) | CNR1CRHR1CRHR2 | |
| SCHEMBL4373504 | 0.79 | CNR1 (0.50) | CNR1CRHR1CRHR2 | |
| SCHEMBL4368598 | 0.79 | CNR2 (0.42) | CNR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1749002-B1 | PYRROLE OR IMIDAZOLE AMIDES FOR TREATING OBESITY | HOFFMANN LA ROCHE (CH) | 2009-05-27 | — | — | EP | claimed |