Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR1 | P21554 | 1/20 | 0.46 |
| ▸ | FAAH | O00519 | 8/20 | 0.39 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4368598 | 0.86 | CNR2 (0.42) | CNR1 | |
| SCHEMBL3916898 | 0.86 | CNR1 (0.60) | CNR1FAAHMEN1NPC1RAB9A | |
| SCHEMBL13717335 | 0.86 | CNR1 (0.60) | CNR1FAAHMEN1NPC1RAB9A | |
| SCHEMBL5570586 | 0.86 | CNR1 (0.60) | CNR1FAAHMEN1NPC1RAB9A | |
| SCHEMBL3916901 | 0.86 | CNR1 (0.60) | CNR1FAAHMEN1NPC1RAB9A | |
| SCHEMBL4372987 | 0.83 | CNR1 (0.39) | CNR1FAAH | |
| SCHEMBL4375089 | 0.82 | CNR1 (0.39) | CNR1FAAH | |
| SCHEMBL4370563 | 0.81 | CNR1 (0.49) | CNR1 | |
| SCHEMBL4367945 | 0.81 | CNR1 (0.49) | CNR1 | |
| SCHEMBL4367963 | 0.80 | CNR1 (0.47) | CNR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1583742-B1 | CB 1 RECEPTOUR INVERSE AGONISTS | HOFFMANN LA ROCHE (CH) | 2009-12-02 | — | — | EP | claimed |