SCHEMBL436827

SCHEMBL436827

O=C(O)c1cc2c3ccc(C(=O)O)c4c(C(=O)O)ccc(c5cccc(c1C(=O)O)c52)c43

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 3/20 0.47
PARP1 P09874 1/20 0.40
TYMS P04818 1/20 0.38
HSD17B10 Q99714 4/20 0.38
HPGD P15428 2/20 0.38
MEN1 O00255 2/20 0.38
CYP2C19 P33261 2/20 0.38
KMT2A Q03164 2/20 0.38
KDM4E B2RXH2 2/20 0.38
ALDH1A1 P00352 2/20 0.38
NR4A1 P22736 1/20 0.38
NR4A2 P43354 1/20 0.38
NR4A3 Q92570 1/20 0.38
GLA P06280 1/20 0.38
CDC25B P30305 2/20 0.38
PTPN1 P18031 1/20 0.37
WDR5 P61964 1/20 0.36
GPR35 Q9HC97 1/20 0.36
CYP2C9 P11712 2/20 0.35
LDHA P00338 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL346772 0.91 HSD17B10 (0.44) CYP1A2PARP1TYMSHSD17B10HPGD
SCHEMBL10350465 0.89 TYMS (0.44) CYP1A2PARP1TYMSHSD17B10HPGD
SCHEMBL15844184 0.89 TYMS (0.44) CYP1A2PARP1TYMSHSD17B10HPGD
SCHEMBL29054769 0.88 HSD17B10 (0.44) CYP1A2HSD17B10HPGDMEN1CYP2C19
SCHEMBL9353923 0.84 HPGD (0.37) CYP1A2PARP1TYMSHSD17B10HPGD
SCHEMBL28774731 0.83 PTPN1 (0.44) CYP1A2TYMSHSD17B10HPGDMEN1
SCHEMBL2173708 0.82 CYP1A2 (0.58) CYP1A2PARP1TYMSHSD17B10HPGD
SCHEMBL6570619 0.80 KMT2A (0.46) CYP1A2HSD17B10HPGDMEN1CYP2C19
SCHEMBL4412297 0.80 CYP1A2 (0.42) CYP1A2PARP1HSD17B10HPGDMEN1
SCHEMBL9135098 0.80 MEN1 (0.42) CYP1A2HSD17B10HPGDMEN1CYP2C19

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 133 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20070009751-A1 Polyamic acid resin composition modified with laminate nanometer silica sheet and polyimide prepared therefrom CHANG CHUN PLASTICS CO., LTD. (TW) 2007-01-11 US claimed
CN-1269905-C Organic and inorganic mixed thin-membrane materials and preparing method thereof CHANGCHUN ARTIFICIAL RESIN FAC (CN) 2006-08-16 CN claimed
US-7005163-B2 Organic-inorganic hybrid film material and its fabrication CHANG CHUN PLASTICS CO., LTD. (TW) 2006-02-28 US claimed
CN-1583881-A Organic and inorganic mixed thin-membrane materials and preparing method thereof CHANGCHUN ARTIFICIAL RESIN FAC (CN) 2005-02-23 CN claimed
US-20040110014-A1 Organic-inorganic hybrid film material and its fabrication CHANG CHUN PLASTICS CO., LTD. (TW) 2004-06-10 US claimed
EP-0362649-B1 Radiation-sensitive compositions and their use BASF AG (DE) 1994-03-02 EP claimed
US-5284734-A Insulating layers and printed circuits; precursors for polyimides and polyquinazolines BASF AKTIENGESELLSCHAFT (DE) 1994-02-08 US claimed
EP-0362649-A2 Radiation-sensitive compositions and their use BASF Aktiengesellschaft (DE) 1990-04-11 EP claimed
EP-3325533-B1 CURABLE BENZOXAZINE COMPOSITIONS HUNTSMAN ADVANCED MAT AMERICAS LLC (US) 2023-09-13 EP disclosed
US-11319410-B2 Precursor for polyimide and use thereof ETERNAL MATERIALS CO., LTD. (TW) 2022-05-03 US disclosed
CN-107995916-B Curable benzoxazine compositions 亨斯迈先进材料美国有限责任公司 2021-08-10 CN disclosed
CN-107189067-B Polyimide precursor and application thereof 长兴材料工业股份有限公司 2021-01-05 CN disclosed
US-10851049-B2 Curable benzoxazine compositions HUNTSMAN ADVANCED MATERIALS AMERICAS LLC (US) 2020-12-01 US disclosed
US-10765008-B2 Metal clad laminate, preparation method thereof, and method for preparing flexible circuit board by using the same ETERNAL MATERIALS CO., LTD. (TW) 2020-09-01 US disclosed
US-4677186-A AMINO DICARBOXYLIC ACID MONOMERS, PROTECITVE COATINGS CIBA-GEIGY CORPORATION (US) 1987-06-30 US disclosed
US-4657832-A HOMO-AND COPOLYMERS, OF POLYIMIDES, POLYAMIDES, POLYESTERS AND OTHERS CIBA-GEIGY CORPORATION (US) 1987-04-14 US disclosed
US-4656116-A CROSSLINKABLE SOLUTIONS OF SOLVENT, POLYIMIDE AND POLYAZIDE CHROMOGEN; PHOTORESISTS; PHOTOLITHOGRAPHY CIBA-GEIGY CORPORATION (US) 1987-04-07 US disclosed
US-4629777-A RADIATION-SENSITIVE, AUTOPHOTOCROSSLINKABLE; FILMS, COATINGS CIBA-GEIGY CORPORATION (US) 1986-12-16 US disclosed
US-4629685-A PROTECTIVE FILMS OR PHOTOGRAPHIC RELIEF IMAGES CIBA-GEIGY CORPORATION (US) 1986-12-16 US disclosed
US-4548891-A PHOTORESISTS; HEAT RESISTANCE; THICKNESS; SHARPNESS CIBA GEIGY CORPORATION (US) 1985-10-22 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10851049-B2 Curable benzoxazine compositions CBX4, CRYZ, CBX8 CYP1A2 1556/4885PARP1 247/4885TYMS 3171/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.