SCHEMBL4368906

SCHEMBL4368906

O=C(O)N1CC=CC=C1c1ccc(O)cc1

nearest known ligand 0.36

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 1/20 0.33
LMNA P02545 1/20 0.33
MAPT P10636 1/20 0.33
RAB9A P51151 1/20 0.33
KMT2A Q03164 1/20 0.33
MMP3 P08254 1/20 0.32
BCL2L1 Q07817 1/20 0.32
ESR1 P03372 1/20 0.32
ESR2 Q92731 1/20 0.32
HSD17B10 Q99714 1/20 0.32
HSD17B1 P14061 1/20 0.32
CA12 O43570 1/20 0.31
CA1 P00915 1/20 0.31
CA2 P00918 1/20 0.31
CA3 P07451 1/20 0.31
TYR P14679 1/20 0.31
DRD1 P21728 1/20 0.31
CA4 P22748 1/20 0.31
CA6 P23280 1/20 0.31
CA5A P35218 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL297498 0.67
SCHEMBL3798872 0.65
SCHEMBL4147880 0.63
SCHEMBL298091 0.63 NOTUM (0.30)
SCHEMBL27642713 0.58 ESR2 (0.43) MEN1LMNAMAPTRAB9AKMT2A
Hydroquinone SCHEMBL8580726 0.58 CA2 (0.67) MEN1LMNAMAPTRAB9AKMT2A
Hydroquinone SCHEMBL4313661 0.58 CA2 (0.67) MEN1LMNAMAPTRAB9AKMT2A
SCHEMBL20993989 0.58 QDPR (0.57) MEN1LMNAMAPTRAB9AKMT2A
Acetic Acid SCHEMBL9809831 0.58 HSD17B1 (0.68) MEN1LMNAMAPTRAB9AKMT2A
SCHEMBL18306856 0.57 ESR1 (0.42) MEN1LMNAMAPTRAB9AKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20090166529-A1 METHOD FOR PREPARING SPECIMEN FOR MASS SPECTROMETRY INTER-UNIVERSITY RESEARCH INSTITUTE CORPORATION NATIONAL INSTITUTES OF NATURAL SCIENCES (JP) 2009-07-02 US disclosed