Known targets — ChEMBL curated mechanism
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
The experimentally established mechanism targets of Phosphoric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB3 known ✓ | P13945 | 1/20 | 0.30 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.37 |
| ▸ | GRIK2 | Q13002 | 1/20 | 0.37 |
| ▸ | GRM1 | Q13255 | 1/20 | 0.37 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | PEPD | P12955 | 1/20 | 0.34 |
| ▸ | TET2 | Q6N021 | 4/20 | 0.33 |
| ▸ | LMNA | P02545 | 4/20 | 0.33 |
| ▸ | BLM | P54132 | 3/20 | 0.33 |
| ▸ | THRB | P10828 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.33 |
| ▸ | GABBR2 | O75899 | 2/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.33 |
| ▸ | TSHR | P16473 | 2/20 | 0.33 |
| ▸ | GABBR1 | Q9UBS5 | 2/20 | 0.33 |
| ▸ | TET3 | O43151 | 1/20 | 0.33 |
| ▸ | TET1 | Q8NFU7 | 1/20 | 0.33 |
| ▸ | GABRR3 | A8MPY1 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22213 | 0.90 | — | — | |
| Hydrochloric Acid SCHEMBL4643783 | 0.87 | — | — | |
| Chloromethane SCHEMBL1507124 | 0.83 | TET2 (0.41) | GRIK1GRIK2GRM1GRM2ALDH1A1 | |
| Methacrylic Acid SCHEMBL28528455 | 0.81 | TDP1 (0.38) | GRIK1GRIK2GRM1GRM2ALDH1A1 | |
| Acrylic Acid SCHEMBL8379454 | 0.79 | ALOX15 (0.56) | GRIK1GRIK2GRM1GRM2ALDH1A1 | |
| Phosphoric Acid SCHEMBL1137737 | 0.78 | PEPD (0.36) | GRIK1GRIK2GRM1GRM2PEPD | |
| Phosphoric Acid SCHEMBL830038 | 0.78 | PEPD (0.36) | GRIK1GRIK2GRM1GRM2PEPD | |
| Nitric Acid SCHEMBL11689138 | 0.77 | CA5A (0.35) | GRIK1GRIK2GRM1GRM2TET2 | |
| SCHEMBL5473510 | 0.77 | PEPD (0.32) | PEPDALOX15HSD17B10 | |
| Phosphoric Acid SCHEMBL951261 | 0.76 | FFAR3 (0.42) | GRIK1GRIK2GRM1GRM2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1811013-B1 | Foamable alcoholic composition | GOJO IND INC (US) | 2009-08-12 | — | — | EP | claimed |
| US-4552692-A | Concentrated composition for cleaning rugs and carpets | GILLESPIE THOMAS W | 1985-11-12 | — | — | US | claimed |
| WO-2013154845-A1 | CURABLE NAIL ENHANCEMENTS | ESSCHEM, INC. (US) | 2013-10-17 | — | — | WO | disclosed |
| US-5958392-A | HAIR CONNDITIONERS COMPRISING A BLEND OF AMPHOTERIC ADDITION POLYMERS CONTAINING AMINE AND CARBOXY OR SULFO GROUPS AND A QUAATERNIZED VINYLPYRROLIDONE/AMINOALCOHOL ACRYLATE COPOLYMER; SOFTNESS; SILKY FEEL | L'OREAL (FR) | 1999-09-28 | — | — | US | disclosed |
| US-4996059-A | Shampoos, conditioners and cosmetics; softness, hold and texture | L'OREAL (FR) | 1991-02-26 | — | — | US | disclosed |
| US-4552692-A | Concentrated composition for cleaning rugs and carpets | GILLESPIE THOMAS W | 1985-11-12 | — | — | US | disclosed |
| US-4009256-A | NOVEL SHAMPOO COMPOSITION CONTAINING A WATER-SOLUBLE CATIONIC POLYMER | NATIONAL STARCH AND CHEMICAL CORPORATION (US) | 1977-02-22 | — | — | US | disclosed |