Methacrylic Acid

Methacrylic Acid

SCHEMBL28528455

C=C(C)C(=O)O.C=C(CCN)C(=O)O

nearest known ligand 0.39

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Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 1/20 0.38
GRIK1 P39086 1/20 0.37
GRIK2 Q13002 1/20 0.37
GRM1 Q13255 1/20 0.37
GRM2 Q14416 1/20 0.37
TET2 Q6N021 4/20 0.35
PAOX Q6QHF9 1/20 0.34
GABRR1 P24046 3/20 0.33
LMNA P02545 2/20 0.33
THRB P10828 2/20 0.33
BLM P54132 2/20 0.33
KMT2A Q03164 2/20 0.33
NPSR1 Q6W5P4 2/20 0.33
TET3 O43151 1/20 0.33
TET1 Q8NFU7 1/20 0.33
GABRR3 A8MPY1 1/20 0.33
GABRP O00591 1/20 0.33
GABRD O14764 1/20 0.33
HDAC3 O15379 1/20 0.33
GABBR2 O75899 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22213 0.90
Chloromethane SCHEMBL1507124 0.88 TET2 (0.41) GRIK1GRIK2GRM1GRM2TET2
Hydrochloric Acid SCHEMBL4643783 0.87
Methacrylic Acid SCHEMBL28799240 0.83 LMNA (0.46) TDP1PAOXGABRR1LMNATHRB
Methacrylic Acid SCHEMBL20917641 0.82 TDP1 (0.47) TDP1GRIK1GRIK2GRM1GRM2
Methacrylic Acid SCHEMBL1399516 0.82 TDP1 (0.47) TDP1GRIK1GRIK2GRM1GRM2
Methacrylic Acid SCHEMBL9300252 0.82 TDP1 (0.47) TDP1GRIK1GRIK2GRM1GRM2
Phosphoric Acid SCHEMBL4368976 0.81 GRIK1 (0.37) GRIK1GRIK2GRM1GRM2TET2
Methacrylic Acid SCHEMBL1399500 0.81 TDP1 (0.43) TDP1PAOXGABRR1LMNATHRB
Methacrylic Acid SCHEMBL8678385 0.79 TDP1 (0.45) TDP1GRIK1GRIK2GRM1GRM2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-108289801-B Oral care gel 高露洁-棕榄公司 2021-01-26 CN disclosed