SCHEMBL4369208

SCHEMBL4369208

COc1ccc(O)c(-c2cc(OC)cc(C(C)(C)C)c2O)c1.OP(O)OCl

nearest known ligand 0.51

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA1 P00915 1/20 0.51
CA2 P00918 1/20 0.51
GAA P10253 6/20 0.45
ALDH1A1 P00352 5/20 0.45
NPC1 O15118 3/20 0.39
MEN1 O00255 4/20 0.36
KMT2A Q03164 4/20 0.36
ALOX15 P16050 4/20 0.36
KDM4E B2RXH2 3/20 0.36
MAPT P10636 3/20 0.36
SMN1; SMN2 Q16637 3/20 0.36
LMNA P02545 2/20 0.36
HPGD P15428 2/20 0.36
RAB9A P51151 2/20 0.36
NPSR1 Q6W5P4 1/20 0.36
MAPK1 P28482 2/20 0.36
THRB P10828 2/20 0.36
RECQL P46063 1/20 0.36
BLM P54132 1/20 0.36
MCL1 Q07820 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16464356 0.92 CA1 (0.54) CA1CA2GAAALDH1A1NPC1
SCHEMBL2262719 0.90 CA1 (0.62) CA1CA2GAAALDH1A1NPC1
SCHEMBL29602570 0.80 CA2 (0.80) CA1CA2GAAALDH1A1MEN1
SCHEMBL240515 0.80 CA2 (0.80) CA1CA2GAAALDH1A1MEN1
SCHEMBL10821898 0.76 CA1 (0.59) CA1CA2GAAALDH1A1ALOX15
SCHEMBL11616701 0.76 NPC1 (0.54) GAAALDH1A1NPC1MEN1KMT2A
SCHEMBL4369204 0.73 CA2 (0.54) CA1CA2GAAALDH1A1ALOX15
SCHEMBL6142004 0.73 ALDH1A1 (0.73) CA1CA2GAAALDH1A1MEN1
SCHEMBL35535 0.73 ALDH1A1 (0.73) CA1CA2GAAALDH1A1MEN1
SCHEMBL29362042 0.73 ALDH1A1 (0.73) CA1CA2GAAALDH1A1MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20150274627-A1 BISPHOSPHITE MIXTURE AND USE THEREOF AS A CATALYST MIXTURE IN HYDROFORMYLATION EVONIK DEGUSSA GMBH (DE) 2015-10-01 US disclosed
US-20090292146-A1 CATALYST PRECURSOR FOR AN Rh COMPLEX CATALYST EVONIK OXENO GMBH (DE) 2009-11-26 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20150274627-A1 BISPHOSPHITE MIXTURE AND USE THEREOF AS A CATALYST MIXTURE IN HYDROFORMYLATION BPGM, PFKFB4, PFKFB3 CA1 568/4885CA2 428/4885GAA 517/4885
US-20090292146-A1 CATALYST PRECURSOR FOR AN Rh COMPLEX CATALYST RFC2, RFC4, RFC5 CA1 2020/4885CA2 2429/4885GAA 1743/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.