Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | OGG1 | O15527 | 1/20 | 0.42 |
| ▸ | CTSD | P07339 | 2/20 | 0.41 |
| ▸ | CA1 | P00915 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
| ▸ | CA9 | Q16790 | 1/20 | 0.41 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.41 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.40 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.40 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.40 |
| ▸ | TAS1R2 | Q8TE23 | 1/20 | 0.40 |
| ▸ | ERCC5 | P28715 | 1/20 | 0.39 |
| ▸ | FEN1 | P39748 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10558954 | 0.80 | ALDH1A1 (0.50) | ALDH1A1KDM4EMAPTPOLBOGG1 | |
| SCHEMBL4377122 | 0.79 | ALDH1A1 (0.50) | ALDH1A1KDM4EMAPTPOLBOGG1 | |
| SCHEMBL4384455 | 0.78 | TAS1R3 (0.60) | ALDH1A1KDM4EMAPTPOLBOGG1 | |
| SCHEMBL3607272 | 0.78 | KLKB1 (0.61) | ALDH1A1KDM4EMAPTPOLBOGG1 | |
| SCHEMBL406614 | 0.77 | POLB (0.69) | ALDH1A1KDM4EMAPTPOLBCTSD | |
| SCHEMBL4387125 | 0.76 | ALDH1A1 (0.42) | ALDH1A1KDM4EMAPTOGG1CTSD | |
| Hydrochloric Acid SCHEMBL2452557 | 0.76 | POLB (0.67) | ALDH1A1KDM4EMAPTPOLBCTSD | |
| SCHEMBL16054667 | 0.75 | TAS1R3 (0.52) | ALDH1A1KDM4EMAPTPOLBOGG1 | |
| SCHEMBL17738209 | 0.75 | KAT6A (0.54) | ALDH1A1KDM4EMAPTPOLBOGG1 | |
| SCHEMBL25364346 | 0.74 | PBRM1 (0.53) | ALDH1A1KDM4EMAPTPOLBOGG1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009109991-A2 | NOVEL HYDRAZIDE CONTAINING TYROSINE KINASE INHIBITORS | SUN PHARMA ADVANCED RESEARCH COMPANY LTD., (IN) | 2009-09-11 | — | — | WO | claimed |