Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2C | P28335 | 4/20 | 0.38 |
| ▸ | SLC6A4 | P31645 | 4/20 | 0.38 |
| ▸ | HPGD | P15428 | 4/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | HTT | P42858 | 2/20 | 0.37 |
| ▸ | TSHR | P16473 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 3/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | CNR2 | P34972 | 2/20 | 0.35 |
| ▸ | CNR1 | P21554 | 1/20 | 0.35 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4562002 | 0.92 | CNR1 (0.39) | TSHRNPC1RAB9ACNR2CNR1 | |
| SCHEMBL4373432 | 0.78 | CNR1 (0.41) | TSHRNPC1RAB9ACNR2CNR1 | |
| SCHEMBL4375154 | 0.77 | PTGER1 (0.43) | HPGDSMN1; SMN2ALDH1A1HTTTSHR | |
| SCHEMBL4372095 | 0.76 | MEN1 (0.43) | HPGDSMN1; SMN2ALDH1A1LMNAMEN1 | |
| SCHEMBL4371328 | 0.75 | GAA (0.42) | HPGDSMN1; SMN2ALDH1A1LMNAHSD17B10 | |
| SCHEMBL4371432 | 0.71 | CNR1 (0.42) | HPGDSMN1; SMN2ALDH1A1HTTTSHR | |
| SCHEMBL4371339 | 0.70 | TP53 (0.43) | HTR2CSLC6A4SMN1; SMN2ALDH1A1TSHR | |
| SCHEMBL4373426 | 0.68 | CNR1 (0.51) | CNR2CNR1 | |
| SCHEMBL4371355 | 0.67 | CNR1 (0.49) | SMN1; SMN2ALDH1A1LMNAHSD17B10MEN1 | |
| SCHEMBL4369561 | 0.66 | KCNH2 (0.41) | HPGDSMN1; SMN2ALDH1A1HSD17B10CNR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1749002-B1 | PYRROLE OR IMIDAZOLE AMIDES FOR TREATING OBESITY | HOFFMANN LA ROCHE (CH) | 2009-05-27 | — | — | EP | claimed |