Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR1 | P21554 | 4/20 | 0.41 |
| ▸ | CNR2 | P34972 | 11/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | RORC | P51449 | 1/20 | 0.36 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.36 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.36 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.36 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.35 |
| ▸ | CRHR1 | P34998 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4373426 | 0.88 | CNR1 (0.51) | CNR1CNR2RORCGRIN1GRIN2B | |
| SCHEMBL4562002 | 0.86 | CNR1 (0.39) | CNR1CNR2TSHRRORCGRIN1 | |
| SCHEMBL4371328 | 0.81 | GAA (0.42) | CNR1CNR2KDM4ENPC1RAB9A | |
| SCHEMBL4371432 | 0.80 | CNR1 (0.42) | CNR1CNR2TSHRRORCGRIN1 | |
| SCHEMBL4369561 | 0.79 | KCNH2 (0.41) | CNR2KDM4E | |
| SCHEMBL4370602 | 0.78 | HTR2C (0.38) | CNR1CNR2TSHRMDM2NPC1 | |
| SCHEMBL4379578 | 0.78 | ALDH1A1 (0.44) | CNR2TSHRKDM4E | |
| SCHEMBL3922441 | 0.77 | CNR1 (0.55) | CNR1CNR2CRHR1 | |
| SCHEMBL4429813 | 0.75 | CNR1 (0.59) | CNR1CNR2CRHR1 | |
| SCHEMBL4368758 | 0.73 | CNR1 (0.51) | CNR1CNR2TSHRRORCKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1749002-B1 | PYRROLE OR IMIDAZOLE AMIDES FOR TREATING OBESITY | HOFFMANN LA ROCHE (CH) | 2009-05-27 | — | — | EP | claimed |