Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 4/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | LIPE | Q05469 | 1/20 | 0.38 |
| ▸ | F11 | P03951 | 3/20 | 0.38 |
| ▸ | KLKB1 | P03952 | 2/20 | 0.38 |
| ▸ | CNR2 | P34972 | 2/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | CNR1 | P21554 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 3/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | USP2 | O75604 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 2/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4372095 | 0.89 | MEN1 (0.43) | GAANPC1RAB9ACNR1ALDH1A1 | |
| SCHEMBL4375072 | 0.88 | CNR1 (0.49) | GAACNR2CNR1 | |
| SCHEMBL4373432 | 0.81 | CNR1 (0.41) | NPC1RAB9ACNR2CNR1KDM4E | |
| SCHEMBL4379578 | 0.81 | ALDH1A1 (0.44) | GAACNR2MAPTALDH1A1KDM4E | |
| SCHEMBL4371355 | 0.80 | CNR1 (0.49) | GAANPC1RAB9ACNR2CNR1 | |
| SCHEMBL3923420 | 0.77 | CNR1 (0.52) | CNR2CNR1MAPTLMNA | |
| SCHEMBL4369561 | 0.76 | KCNH2 (0.41) | GAALIPECNR2ALDH1A1KDM4E | |
| SCHEMBL4370602 | 0.75 | HTR2C (0.38) | GAANPC1RAB9ACNR2CNR1 | |
| SCHEMBL3917725 | 0.72 | CNR1 (0.51) | CNR2CNR1 | |
| SCHEMBL3920028 | 0.71 | CNR1 (0.51) | CNR2CNR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1749002-B1 | PYRROLE OR IMIDAZOLE AMIDES FOR TREATING OBESITY | HOFFMANN LA ROCHE (CH) | 2009-05-27 | — | — | EP | claimed |